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U2625

Uric acid

Name: Uric acid
Brand: SIGMA

≥99%, crystalline

Synonym(s):

2,6,8-Trihydroxypurine

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About This Item

Empirical Formula (Hill Notation):

C₅H₄N₄O₃

CAS Number:

69-93-2

Molecular Weight:

168.11

UNSPSC Code:

12352005

NACRES:

NA.55

PubChem Substance ID:

24900634

EC Number:

200-720-7

Beilstein/REAXYS Number:

156158

MDL number:

MFCD00005712

Assay:

≥99%

Form:

crystalline

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Properties

Quality Segment

100, 200

assay

≥99%

form

crystalline

mp

>300 °C (lit.)

SMILES string

O=C1NC(=O)C2=C(N1)NC(=O)N2

InChI

1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)

InChI key

LEHOTFFKMJEONL-UHFFFAOYSA-N

Description

Application

Uric acid has been used:

in inducing hyperuricemia in mice
as a component of digestion fluid for the simulation of in vitro human digestion model
in selectivity test of the glucose sensor in sweat-based diabetes monitoring

Biochem/physiol Actions

Uric acid is an insoluble catabolite produced by adenine and guanine metabolism. Accumulation of uric acid leads to gout, hyperuricemia, arthritis and renal failure. Elevated uric acid levels contributes to hypertension and pathogenesis of cardiovascular disease. Low uric acid levels associated with Parkinson′s disease and multiple sclerosis, may elicit protective functionality. High levels of uric acid in patients with chronic obstructive pulmonary disease (COPD) may serve as potential marker for diagnosis.

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Storage Class

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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