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U6375

Uridine 5′-monophosphate disodium salt

Name: Uridine 5&#8242;-monophosphate disodium salt
Brand: SIGMA

≥99%, (chemical), powder

Synonym(s):

5′-UMP-Na₂, U 5′-P, UMP, Uridylic acid disodium salt

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About This Item

Empirical Formula (Hill Notation):

C₉H₁₁N₂Na₂O₉P

CAS Number:

3387-36-8

Molecular Weight:

368.15

NACRES:

NA.26

PubChem Substance ID:

24900433

UNSPSC Code:

12352204

EC Number:

222-211-9

MDL number:

MFCD00006525

Beilstein/REAXYS Number:

3582885

Assay:

≥99%

Biological source:

(chemical)

Form:

powder

Solubility:

water: 50 mg/mL, clear, colorless

Storage temp.:

−20°C

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Product Name

Uridine 5′-monophosphate disodium salt, ≥99%

biological source

(chemical)

Quality Level

200

assay

≥99%

form

powder

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])([O-])=O)N2C=CC(=O)NC2=O

InChI

1S/C9H13N2O9P.2Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1

InChI key

KURVIXMFFSNONZ-WFIJOQBCSA-L

Related Categories

Biochemicals

Nucleosides and Nucleotides

Phosphates

General description

Uridine 5′-monophosphate is a pyrimidine mononucleotide. It is formed by decarboxylation of orotidine 5′-monophosphate. UMP is further converted to UTP (uridine 5′-triphosphate) using kinases.

Application

Uridine 5′-monophosphate disodium salt has been used to study the effect of pyrimidine synthesis inhibitor, 5-azacytidine, on cholesterol and lipid metabolism. It has been used to study the effect of nucleotides on growth of specific intestinal bacteria.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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The epigenetic drug 5-azacytidine interferes with cholesterol and lipid metabolism.

Poirier S, et al.

The Journal of Biological Chemistry, 289, 18736-18751 (2014)

Adams RLP, et al.

The Biochemistry of the Nucleic Acids (2013)

N-Propyl-N'-2-pyridylurea-modified silica as mixed-mode stationary phase with moderate weak anion exchange capacity and pH-dependent surface charge reversal.

Stefanie Bäurer et al.

Journal of chromatography. A, 1560, 45-54 (2018-05-24)

Herein, we present a novel silica-based stationary phase modified with N-propyl-N'-2-pyridylurea selector. Due to the weakly basic properties of the pyridine selector and the presence of residual silanols after selector immobilization, a zwitterionic surface with a pI observed at approximately

Nucleotides modify growth of selected intestinal bacteria in vitro.

Sauer N, et al.

Livestock Science, 133, 161-163 (2010)

Umami synergy as the scientific principle behind taste-pairing champagne and oysters.

Charlotte Vinther Schmidt et al.

Scientific reports, 10(1), 20077-20077 (2020-11-20)

Food and flavour pairing are commonly used as an empirically based phenomenology by chefs and food innovators for creating delicious dishes. However, there is little if any science behind the pairing systems used, and it appears that pairing is determined

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Global Trade Item Number

SKU	GTIN
U6375-5G	04061837409844
U6375-10G	04061837409820
U6375-10MG	04061831169508
U6375-1G	04061837409837
U6375-25MG	04061831160383

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