U6758
UCL 2077
≥98% (HPLC), solid
别名:
(3-Triphenylmethylaminomethyl)pyridine
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关于此项目
经验公式（希尔记法）:
C25H22N2
化学文摘社编号:
分子量:
350.46
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Quality Segment
assay
≥98% (HPLC)
form
solid
color
white
solubility
DMSO: soluble >20 mg/mL, H2O: insoluble
SMILES string
C(NC(c1ccccc1)(c2ccccc2)c3ccccc3)c4cccnc4
InChI
1S/C25H22N2/c1-4-12-22(13-5-1)25(23-14-6-2-7-15-23,24-16-8-3-9-17-24)27-20-21-11-10-18-26-19-21/h1-19,27H,20H2
InChI key
PQFNWDHABGBCHB-UHFFFAOYSA-N
Application
UCL 2077 has been used for slow afterhyperpolarization (sAHP) studies in thalamic paraventricular nucleus (PVT) neurons. UCL 2077 has also been used for studying its effects on the increase in excitability of hippocampal pyramidal cells.
Biochem/physiol Actions
UCL 2077 is a slow afterhyperpolarization (sAHP) channel blocker.
Preparation Note
UCL 2077 is soluble in DMSO at a concentration >20 mg/ml and is insoluble in water.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves