U9382
Ubiquitin-Carrier Protein H10 human
≥95% (SDS-PAGE), recombinant, expressed in E. coli (histidine-tagged), buffered aqueous glycerol solution
Synonym(s):
UbcH10
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About This Item
Form:
buffered aqueous glycerol solution
Assay:
≥95% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli (histidine-tagged)
Mol wt:
~20 kDa
biological source
human
Quality Segment
recombinant
expressed in E. coli (histidine-tagged)
assay
≥95% (SDS-PAGE)
form
buffered aqueous glycerol solution
mol wt
~20 kDa
technique(s)
ligand binding assay: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... UBE2C(11065)
General description
Manufactured for Sigma by Boston Biochem., Inc.
Application
Ubiquitin-Carrier Protein H10 (UbcH10) human may be used to study the role of ubiquitin-proteasome system in pathogenesis of human diseases.
Biochem/physiol Actions
In conjunction with anaphase-promoting complex, catalyzes both cyclin A and cyclin B destruction.
In conjunction with the anaphase-promoting complex, the protein catalyzes the destruction of both cyclin A and cyclin B.
Ubiquitin-Carrier Protein H10 human also referred to as UbcH10 is a recombinant protein that catalyzes the destruction of cyclin A as well as cyclin B along with the anaphase promoting complex and hence plays a pivotal role in controlling the cell exit from mitosis.
Physical form
Solution in 50 mM HEPES, pH 8.0, 125 mM NaCl, and 1 mM DTT in 10% glycerol.
wgk
WGK 1
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