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UC448

Paracetamol sulfate potassium salt

Name: Paracetamol sulfate potassium salt
Brand: SIGMA

≥97% (HPLC), analgesic agent, solid

Synonym(s):

4-Acetamidophenol sulfate ester potassium salt, Acetaminophen sulfate potassium salt, N-(4-Sulfoxyphenyl)acetamide monopotassium salt

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About This Item

Empirical Formula (Hill Notation):

C₈H₈KNO₅S

CAS Number:

32113-41-0

Molecular Weight:

269.32

UNSPSC Code:

12161501

PubChem Substance ID:

329827671

NACRES:

NA.77

MDL number:

MFCD01631667

Assay:

≥97% (HPLC)

Form:

solid

Quality level:

200

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Product Name

Paracetamol sulfate potassium salt, solid, ≥97% (HPLC)

Quality Level

200

assay

≥97% (HPLC)

form

solid

color

white to off-white

mp

163 °C

solubility

H₂O: soluble

storage temp.

2-8°C

SMILES string

[K+].CC(=O)Nc1ccc(OS([O-])(=O)=O)cc1

InChI

1S/C8H9NO5S.K/c1-6(10)9-7-2-4-8(5-3-7)14-15(11,12)13;/h2-5H,1H3,(H,9,10)(H,11,12,13);/q;+1/p-1

InChI key

AJYPYWFCUWHZMZ-UHFFFAOYSA-M

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Bioactive Small Molecule Inhibitors

Bioactive Small Molecules

General description

Paracetamol is an aminophenol derivative. It functions as an analgesic and antipyretic drug, which has weak inflammatory effect. Paracetamol is used to treat pyrexia and mild to moderate pain. It might inhibit atherosclerosis through its antioxidant activity.

Application

Paracetamol sulfate potassium salt has been used as a standard for HPLC assays of acetaminophen.

Biochem/physiol Actions

Phase II metabolite of paracetamol.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Preparation Note

Paracetamol sulfate potassium salt is soluble in water.

Other Notes

Occasionally, it may be necessary to supply as the sodium salt

pictograms

GHS05,GHS07

signalword

Danger

hcodes

H315,H317,H318,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Immune thrombocytopenia resulting from sensitivity to metabolites of naproxen and acetaminophen.

D Bougie et al.

Blood, 97(12), 3846-3850 (2001-06-05)

In patients suspected of having drug-induced immune thrombocytopenia, antibodies reactive with normal platelets in the presence of the suspect drug can sometimes be identified, but negative results are often obtained. One reason for this is that drug metabolites, formed in

Paracetamol: past, present, and future.

Prescott LF

American Journal of Therapeutics, 7(2), 143-147 (2000)

Spectrophotometric determination of paracetamol in urine with tetrahydroxycalix[4]arene as a coupling reagent and preconcentration with triton X-114 using cloud point extraction.

Hayati Filik et al.

Chemical & pharmaceutical bulletin, 54(6), 891-896 (2006-06-07)

In the present paper, conventional spectrophotometry in conjunction with cloud point extraction-preconcentration were investigated as alternative methods for paracetamol (PCT) assay in urine samples. Cloud point extraction (CPE) was employed for the preconcentration of p-aminophenol (PAP) prior to spectrophotometric determination

Investigating paracetamol pharmacokinetics using venous and capillary blood and saliva sampling.

Anneliese M Rittau et al.

The Journal of pharmacy and pharmacology, 64(5), 705-711 (2012-04-05)

The aim of this study was to develop, validate and apply a high performance liquid chromatography (HPLC) assay for analysis of paracetamol, paracetamol glucuronide and paracetamol sulfate in plasma (venous and capillary) and saliva to study paracetamol pharmacokinetics in healthy

Pharmacokinetics of intravenous paracetamol in elderly patients.

Antti Liukas et al.

Clinical pharmacokinetics, 50(2), 121-129 (2011-01-19)

Intravenous paracetamol (N-acetyl-paraminophenol, acetaminophen) is a widely used nonopioid analgesic which has become popular in the treatment of pain in many patient groups, including the elderly. Although intravenous paracetamol has been studied widely in clinical analgesia studies, there is little

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Global Trade Item Number

SKU	GTIN
UC448-5MG	04061837410284
UC448-10MG	04061832932286

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