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V0131

Vasoactive Intestinal Peptide Fragment 1-12 human, porcine, rat

≥97% (HPLC)

Synonym(s):

VIP 1-12

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About This Item

Empirical Formula (Hill Notation):
C61H88N18O22
CAS Number:
120928-03-2
Molecular Weight:
1425.46
UNSPSC Code:
12352200
PubChem Substance ID:
24900690
NACRES:
NA.26
MDL number:
MFCD00133921
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Product Name

Vasoactive Intestinal Peptide Fragment 1-12 human, porcine, rat, ≥97% (HPLC)

Quality Level

200

assay

≥97% (HPLC)

form

solid

UniProt accession no.

P01282

application(s)

cell analysis

storage temp.

−20°C

SMILES string

CC(C)C(NC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(Cc2ccccc2)C(=O)NC(C(C)O)C(=O)NC(CC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(C(C)O)C(=O)NC(CCCNC(N)=N)C(O)=O

InChI

1S/C61H88N18O22/c1-27(2)46(77-49(89)28(3)69-51(91)40(22-44(85)86)73-56(96)42(25-80)76-50(90)35(62)20-33-24-66-26-68-33)57(97)74-38(18-31-10-7-6-8-11-31)55(95)79-48(30(5)82)59(99)75-41(23-45(87)88)53(93)72-39(21-43(63)84)52(92)71-37(19-32-13-15-34(83)16-14-32)54(94)78-47(29(4)81)58(98)70-36(60(100)101)12-9-17-67-61(64)65/h6-8,10-11,13-16,24,26-30,35-42,46-48,80-83H,9,12,17-23,25,62H2,1-5H3,(H2,63,84)(H,66,68)(H,69,91)(H,70,98)(H,71,92)(H,72,93)(H,73,96)(H,74,97)(H,75,99)(H,76,90)(H,77,89)(H,78,94)(H,79,95)(H,85,86)(H,87,88)(H,100,101)(H4,64,65,67)

InChI key

OZQVVUDUPMJWPH-UHFFFAOYSA-N

Gene Information

human ... VIP(7432)

Biochem/physiol Actions

Ligand for CD4 receptor.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
118K8724
048K1292
067K1846
076K13691
095K11621

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K J Sung et al.
Neuropeptides, 33(6), 435-446 (2000-02-05)
It is well known that psoriasis, an immunogenetic cutaneous disorder whose major pathogenic findings are epidermal hyperplasia and T-cell infiltration, is aggravated by psychological stresses. Although the exact mechanism is not yet clarified, antidromic secretion of neuropeptides by cutaneous nerve
M Ichinose et al.
Regulatory peptides, 54(2-3), 457-466 (1994-12-15)
The effect of VIP on phagocytosis in peritoneal macrophages was examined by means of flow cytometry (FCM). This assay revealed that VIP suppressed phagocytosis in a dose-dependent manner. VIP(1-12) did not suppress phagocytosis. VIP(10-28) was more suppressive than VIP(1-28). A
S Chakder et al.
The Journal of pharmacology and experimental therapeutics, 266(1), 392-399 (1993-07-01)
Because no significant information exists regarding the structure-activity of vasoactive intestinal polypeptide (VIP) to gut smooth muscle, we performed functional studies in vitro on opossum internal anal sphincter (IAS) smooth muscle strips and supplemented them with binding studies to assess
F Séjourné et al.
The American journal of physiology, 273(1 Pt 2), R287-R292 (1997-07-01)
The purpose of this study was to begin to determine the mechanisms underlying vasodilation elicited by vasoactive intestinal peptide (VIP) in sterically stabilized liposomes (SSL) in the in situ peripheral microcirculation. Using intravital microscopy, we found that suffusion of VIP
P Sacerdote et al.
Journal of neuroscience research, 18(1), 102-107 (1987-01-01)
A five-amino-acid (TDNYT) sequence of vasoactive intestinal polypeptide (VIP) shares homology with the proposed attachment sequences of the human immunodeficiency virus (HIV). Synthetic peptides with these sequences have previously been shown to block viral envelope (gp120) binding and HIV infectivity

Global Trade Item Number

SKUGTIN
V0131-.1MG04061832823010
V0131-1MG04061826286326

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