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Merck
CN

V0883

Val-Ala-Pro-Gly acetate salt

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C15H26N4O5 · xC2H4O2
CAS Number:
Molecular Weight:
342.39 (free base basis)
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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InChI

1S/C15H26N4O5/c1-8(2)12(16)14(23)18-9(3)15(24)19-6-4-5-10(19)13(22)17-7-11(20)21/h8-10,12H,4-7,16H2,1-3H3,(H,17,22)(H,18,23)(H,20,21)

SMILES string

CC(C)C(N)C(=O)NC(C)C(=O)N1CCCC1C(=O)NCC(O)=O

InChI key

PPINMSZPTPRQQB-UHFFFAOYSA-N

assay

≥97% (HPLC)

storage temp.

−20°C

Application

Serves as a quantitative marker for human elastins.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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L S Price et al.
Matrix (Stuttgart, Germany), 13(4), 307-311 (1993-07-01)
Thermolysin digests of human elastins were examined for reliable elastin peptide markers as determined by HPLC followed by amino acid sequencing of promising peaks. The tetrapeptide VAPG was found to occur in the early portion of the chromatogram in a
Andrea S Gobin et al.
Journal of biomedical materials research. Part A, 67(1), 255-259 (2003-10-01)
The elastin-derived peptide val-ala-pro-gly (VAPG) may be useful as a biospecific cell adhesion ligand for smooth muscle cells. By grafting the peptide sequence into a hydrogel material, we were able to assess its effects on smooth muscle cell adhesion and
Peter Pocza et al.
International journal of cancer, 122(9), 1972-1980 (2007-12-14)
Melanomas containing more elastin are associated with higher stages of the disease. The interaction between elastin-derived peptides and melanoma cells appears to play an important role in the progression of melanomas. The effects of the elastin-derived peptides VGVAPG and VAPG

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