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Merck
CN

V2140

Anti-VRK2 antibody produced in rabbit

~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-Vaccinia related kinase 2, Anti-Vaccinia virus B1R-related kinase 2

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About This Item

UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~58 kDa

species reactivity

human

concentration

~1.5 mg/mL

technique(s)

western blot: 0.5-1.0 μg/mL using HEK-293T cell lysate expressing human VRK2

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... VRK2(7444)

General description

VRK2 is a serine/threonine kinase that is expressed in the nucleus and cytoplasm of cells. This kinase modulates autophagy, cell cycle, MAPK-mediated signaling pathways and cell death. Decreased levels of VRK2 have been associated with breast cancer . Anti-VRK2 antibody is specific for human VRK2. In immunoblotting, detection of the VRK2 band is specifically inhibited by the VRK2 immunizing peptide.

Application

Anti-VRK2 antibody is suitable for use in western blot (0.5-1.0 μg/mL using HEK-293T cell lysate expressing human VRK2) and immunoblot (approx. 58 kDa).

Physical form

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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