Skip to Content
Merck
CN

V9263

Monoclonal Anti-Vascular Cell Adhesion Molecule 1 antibody produced in mouse

~1 mg/mL, clone 1.4C3, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-VCAM-1

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD00240671

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Monoclonal Anti-Vascular Cell Adhesion Molecule 1 antibody produced in mouse, ~1 mg/mL, clone 1.4C3, purified immunoglobulin, buffered aqueous solution

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1.4C3, monoclonal

form

buffered aqueous solution

mol wt

antigen 110 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 2-4 μg/mL using human tonsil tissue
immunohistochemistry (frozen sections): 2-4 μg/mL using human tonsil tissue
western blot: suitable

isotype

IgG1

UniProt accession no.

P19320

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

200

Gene Information

human ... VCAM1(7412)

Application

Monoclonal anti-vascular cell adhesion molecule 1 antibody can be used in immunoblotting and western blotting.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

VCAM-1(Vascular Cell Adhesion Molecule-1) belongs to immunoglobulin-related gene superfamily of adhesion molecules and is a 110kD cell surface integral membrane glycoprotein. It is expressed mainly by cytokine-activated endothelium and plays a pivotal role in numerous immunological and inflammatory responses. Monoclonal anti-vascular cell adhesion molecule 1 antibody can be used in immunohistochemistry for formalin-fixed, paraffin-embedded tissue sections. Mouse anti-vascular cell adhesion molecule 1 antibody reacts specifically with human vascular cell adhesion molecule-1 (CD106 or INCAM-110).

Immunogen

stimulated HUVEC cells and mouse NS1 cells.

Physical form

Solution in phosphate buffered saline containing 0.08% sodium azide.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SLBR6997
SLBR5484
SLBQ3108
SLBB0120
061M1845

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Darren G Woodside et al.
Journal of immunology (Baltimore, Md. : 1950), 176(8), 5041-5049 (2006-04-06)
Cell adhesion mediated by the interaction between integrin alpha4beta1 and VCAM-1 is important in normal physiologic processes and in inflammatory and autoimmune disease. Numerous studies have mapped the alpha4beta1 binding sites in VCAM-1 that mediate cell adhesion; however, little is
A G Kumar et al.
Journal of immunology (Baltimore, Md. : 1950), 153(9), 4088-4098 (1994-11-01)
Vascular cell adhesion molecule-1 (VCAM-1) is a member of the Ig superfamily that shows increased expression in a number of pathologic conditions. The role of VCAM-1 in human disease remains undefined and murine models are being extensively studied to help
Amarylis C B A Wanschel et al.
Biomolecules, 11(1) (2021-01-13)
Endothelial dysfunction precedes atherosclerosis and is an independent predictor of cardiovascular events. Cholesterol levels and oxidative stress are key contributors to endothelial damage, whereas high levels of plasma high-density lipoproteins (HDL) could prevent it. Cholesteryl ester transfer protein (CETP) is

Articles

Angiogenesis Assays

Cell based angiogenesis assays to analyze new blood vessel formation for applications of cancer research, tissue regeneration and vascular biology.

血管生成测定

在癌症研究、组织再生和血管生物学应用中通过以细胞为基础的血管生成检测来分析新血管的形成。

Related Content

Data Sheet - V9263

Instructions

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service