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About This Item
Linear Formula:
C27H26N2O3 · CH3SO3H
CAS Number:
Molecular Weight:
522.61
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
SMILES string
CS(O)(=O)=O.Cc1c(C(=O)c2cccc3ccccc23)c4cccc5OC[C@H](CN6CCOCC6)n1c45
form
solid
optical activity
[α]/D −48.0°, c = 0.246 in DMSO(lit.)
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
color
off-white
solubility
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.4 mg/mL, DMSO: soluble, methanol: soluble
Biochem/physiol Actions
Inactive enantiomer of WIN 55,212-2.
Legal Information
Manufactured and sold with the permission of Sterling Winthrop.
Disclaimer
Hygroscopic
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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U Herzberg et al.
Neuroscience letters, 221(2-3), 157-160 (1997-01-17)
The effects of a high affinity cannabinoid receptor agonist were evaluated in rats subjected to chronic constriction injury of the sciatic nerve (CCI) or a sham operation. Intraperitoneal (i.p.) injections of the active, but not the inactive enantiomer, alleviated the
X Pan et al.
Molecular pharmacology, 49(4), 707-714 (1996-04-01)
Modulation of neuronal ion channels by the cloned rat brain CB1 cannabinoid receptor was investigated with the use of a heterologous neuronal expression system. Transient expression of the rat brain CB1 cannabinoid receptor was accomplished through microinjection of in vitro
A Richter et al.
European journal of pharmacology, 264(3), 371-377 (1994-11-03)
The effects of the novel high affinity cannabinoid receptor agonist (+)-WIN 55,212-2 ((R)-4,5-dihydro-2-methyl-4(4-morphoinylmethyl)-1-(1-naphthalen ylcarbonyl)-6H-pyrrolo[3,2,1-ij]quinolin-6-one) on severity of dystonia were investigated in mutant Syrian hamsters with primary generalized dystonia. Following injections of (+)-WIN 55,212-2 (1.0-5.0 mg/kg i.p.) a dose-dependent reduction of
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