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WH0007010M2

Monoclonal Anti-TEK antibody produced in mouse

Name: Monoclonal Anti-TEK antibody produced in mouse
Brand: SIGMA

clone 3F8, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-CD202B, Anti-TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal), Anti-TIE2, Anti-VMCM, Anti-VMCM1

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD02264171

Conjugate:

unconjugated

Clone:

3F8, monoclonal

Application:

ELISA (i), WB

Citations:

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Properties

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

3F8, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

indirect ELISA: suitable, western blot: 1-5 μg/mL

isotype

IgG2aκ

GenBank accession no.

BC035514

UniProt accession no.

Q02763

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TEK(7010)

Description

General description

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. (provided by RefSeq)

Immunogen

TEK (AAH35514, 701 a.a. ~ 800 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
AFSHELVTLPESQAPADLGGGKMLLIAILGSAGMTCLTVLLAFLIILQLKRANVQRRMAQAFQNVREEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWND

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

常规特殊物品

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Certificates of Analysis (COA)

Lot/Batch Number

07075-3F8

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Global Trade Item Number

SKU	GTIN
WH0007010M2-100UG	04061829611835