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Merck
CN

WH0007360M1

Sigma-Aldrich

Monoclonal Anti-UGP2 antibody produced in mouse

clone 3H3, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-UDP-glucose pyrophosphorylase 2, Anti-UDPG, Anti-UDPGP2, Anti-UGPP2, Anti-pHC379

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

3H3, monoclonal

form

buffered aqueous solution

species reactivity

human, rat, mouse

technique(s)

indirect ELISA: suitable
western blot: 1-5 μg/mL

isotype

IgG2aκ

GenBank accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... UGP2(7360)

General description

The UDP-glucose pyrophosphorylase 2 (UGP2 ) gene is localized on human chromosome 2p15. It has a crucial role in carbohydrate metabolism. Its product uridine diphosphate-glucose (UDP-glucose) acts as a precursor for sugar nucleotides and is involved in various pathways. The enzyme is involved in the conversion of glucose-1-phosphate and MgUTP to UDP-glucose and MgPPi.

Immunogen

UGP2 (NP_001001521, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MSQDGASQFQEVIRQELELSVKKELEKILTTASSHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIKARGLPDNI

Application

Monoclonal Anti-UGP2 antibody produced in mouse has been used in Western blotting.

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Octamerization is essential for enzymatic function of human UDP-glucose pyrophosphorylase.
Glycobiology (2013)
Pathogenic variants screening in seventeen candidate genes on 2p15 for association with ankylosing spondylitis in a Han Chinese population
Mengmeng Wang
PLoS ONE (2017)
Sequence differences between human muscle and liver cDNAs for UDPglucose pyrophosphorylase and kinetic properties of the recombinant enzymes expressed in Escherichia coli.
European Journal of Biochemistry (1996)
Novel Proteomic Biomarker Panel for Prediction of Aggressive Metastatic Hepatocellular Carcinoma Relapse in Surgically Resectable Patients
Gek San Tan
Journal of Proteome Research, 13(11) (2014)

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