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Merck
CN

X1251

Xylazine hydrochloride

≥99.0% (HPLC), powder, sedative

Synonym(s):

2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine hydrochloride, 5,6-Dihydro-2-(2,6-xylidino)-4H-1,3-thiazine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H16N2S · HCl
CAS Number:
23076-35-9
Molecular Weight:
256.79
NACRES:
NA.77
PubChem Substance ID:
24277813
UNSPSC Code:
12352200
MDL number:
MFCD00058196
Beilstein/REAXYS Number:
6448471

Key Documents

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Product Name

Xylazine hydrochloride, ≥99.0% (HPLC)

InChI

1S/C12H16N2S.ClH/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12;/h3,5-6H,4,7-8H2,1-2H3,(H,13,14);1H

SMILES string

Cl[H].Cc1cccc(C)c1NC2=NCCCS2

InChI key

QYEFBJRXKKSABU-UHFFFAOYSA-N

assay

≥99.0% (HPLC)

storage temp.

−20°C

Quality Level

200

Gene Information

human ... ADRA2A(150), ADRA2B(151), ADRA2C(152)

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Application

Xylazine hydrochloride has been used to anesthetize rats/mice.

Biochem/physiol Actions

α2-Adrenergic receptor agonist, sedative, muscle relaxant.
Xylazine is used as a sedative in goats as it is safe, active and a cheap drug. It is a centrally acting drug, which exhibits muscle relaxant and analgesic properties.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000382195
0000382196
0000320046
0000382195
0000382196

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Pain
Handbook of Veterinary Neurology (2011)
[alpha]-actin Down Regulation and Perforin Loss in Uterine Natural Killer Cells From LPS-Treated Pregnant Mice
Zavan B, et al.
Physiological Research, 64(3), 427-427 (2015)
Anesthesia and analgesia
The laboratory rabbit, guinea pig, hamster, and other rodents., 33-56 (2012)
Effect of xylazine hydrochloride (Rompun(\textregistered)) on Sokoto red goats
Mohammed, A and Yelwa, HA
Small Ruminant Research, 12(1), 107-113 (1993)
Eva Wex et al.
British journal of pharmacology, 172(14), 3537-3547 (2015-04-01)
β2 -adrenoceptor agonists are widely used in the management of obstructive airway diseases. Besides their bronchodilatory effect, several studies suggest inhibitory effects on various aspects of inflammation. The aim of our study was to determine the efficacy of the long-acting
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Product Information Sheet - X1251

Product Information Sheet

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