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Merck
CN

X3627

Sigma-Aldrich

Xanthine sodium salt

≥99%, synthetic (organic)

Synonym(s):

2,6-Dihydroxypurine

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About This Item

Empirical Formula (Hill Notation):
C5H3N4NaO2
CAS Number:
Molecular Weight:
174.09
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
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Product Name

Xanthine sodium salt, suitable for cell culture, ≥99%

biological source

synthetic (organic)

Quality Level

Assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

≤4% methanol

solubility

1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to light yellow

SMILES string

[Na].O=C1NC(=O)c2[nH]cnc2N1

InChI

1S/C5H4N4O2.Na.H/c10-4-2-3(7-1-6-2)8-5(11)9-4;;/h1H,(H3,6,7,8,9,10,11);;

InChI key

JAZQMXVZANZJSO-UHFFFAOYSA-N

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General description

Xanthine is commonly present in tea, coffee and cocoa. Xanthine is a nitrogenous compound present in blood and urine.

Application

Xanthine sodium salt has been used:
  • as a component in superoxide dismutase (SOD)-inhibitable ferricytochrome c reduction assay
  • as a component in selection of chimeric Modified Vaccinia virus Ankara (MVA)
  • as a substrate in the reaction mixture for xanthine oxidase assay

Biochem/physiol Actions

Xanthine possesses therapeutic properties. It acts as a mild stimulant of the central nervous system.

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

STOT SE 2

Target Organs

Eyes

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Uric acid-lowering effect and intestinal permeability of Kampo medicine, Hachimijiogan, Yokuininto and Goshakusan
Lee SH, et al.
European journal of integrative medicine, 20(1), 193-199 (2018)
Construction of FWPV Chimaeric MVA
Buttigieg KR and Skinner MA
Bio-protocol, 5(1), 65-80 (2015)
Modern Pharmacology with Clinical Applications, 351-351 (2004)
Rau's Respiratory Care Pharmacology - E-Book (2013)
Yifan Wang et al.
Nature communications, 11(1), 5258-5258 (2020-10-18)
Macrophages play an essential role in the early immune response against Toxoplasma and are the cell type preferentially infected by the parasite in vivo. Interferon gamma (IFNγ) elicits a variety of anti-Toxoplasma activities in macrophages. Using a genome-wide CRISPR screen

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Uric acid present in animal sera impacts serum-supplemented classical cell culture systems, influencing cell culture performance.

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