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About This Item
Empirical Formula (Hill Notation):
C18H24O5
CAS Number:
Molecular Weight:
320.38
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Product Name
α-Zearalenol,
assay
≥98% (HPLC)
Quality Segment
form
powder
solubility
methanol: 9.80-10.20 mg/mL, clear, colorless to faintly yellow
storage temp.
−20°C
SMILES string
C[C@H]1CCC[C@H](O)CCC\C=C\c2cc(O)cc(O)c2C(=O)O1
InChI
1S/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,14,19-21H,2,4-6,8-9H2,1H3/b7-3+/t12-,14+/m0/s1
InChI key
FPQFYIAXQDXNOR-QDKLYSGJSA-N
Gene Information
rat ... Ar(24208)
Application
α-Zearalenol has been used:
- as an analytical standard in the quantification of mycotoxins from animal feed
- to evaluate its oestrogenic activity on boar sperm motility , as an anti-oestrogen control in MCF7 cells
- as a reference standard in a liquid chromatography-negative ion electrospray tandem mass spectrometry with atmospheric pressure chemical ionization (LCAPCI/MS/MS) for bovine follicular fluids (FFs) quantification
Biochem/physiol Actions
α-Zearalenol (α-ZOL) is a catabolite of zearalenone, synthesized majorly in granulosa cells, intestine and liver in pigs. It has estrogenic functionality. α-ZOL inhibits sperm motility in horse possibly by eliciting genotoxic effect. α-ZOL displays higher affinity towards estrogenic receptors.
signalword
Danger
Hazard Classifications
Aquatic Chronic 3 - Carc. 2 - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B - STOT SE 2
Storage Class
8B - Non-combustible, corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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