Z4277
Zileuton
≥98% (HPLC), 5-Lipoxygenase inhibitor, powder
Synonym(s):
(±)-N-hydroxy-N-(1-benzo[b]thien-2-ylethyl)urea
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C11H12N2O2S
CAS Number:
Molecular Weight:
236.29
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Product Name
Zileuton, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: ≥20 mg/mL at ~60 °C (warm up to 60 C for 5min)
originator
Abbott
storage temp.
room temp
SMILES string
CC(N(O)C(N)=O)c1cc2ccccc2s1
InChI
1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)
InChI key
MWLSOWXNZPKENC-UHFFFAOYSA-N
Gene Information
human ... ALOX5(240)
Biochem/physiol Actions
Zileuton is a 5-Lipoxygenase inhibitor.
Zileuton is an anti-asthmatic, an inhibitor of 5-lipoxygenase; the initial enzyme in the biosynthesis of leukotrienes from arachidonic acid.
Features and Benefits
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Still not finding the right product?
Explore all of our products under Zileuton
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Articles
Discover Bioactive Small Molecules for Lipid Signaling Research
Norwin Kubick et al.
Molecules (Basel, Switzerland), 25(9) (2020-05-10)
Repurposing drugs to target M1 macrophages inflammatory response in depression constitutes a bright alternative for commonly used antidepressants. Depression is a significant type of mood disorder, where patients suffer from pathological disturbances associated with a proinflammatory M1 macrophage phenotype. Presently
Hee Young Kim et al.
eLife, 12 (2024-07-09)
Trained immunity is the long-term functional reprogramming of innate immune cells, which results in altered responses toward a secondary challenge. Despite indoxyl sulfate (IS) being a potent stimulus associated with chronic kidney disease (CKD)-related inflammation, its impact on trained immunity
Lalit Pukhrambam Singh et al.
JOJ ophthalmology, 8(5), 77-85 (2022-02-22)
Diabetic retinopathy (DR) is a devastating disease leading to blindness among majority of working adults around the globe. Nonetheless, an effective treatment or cure for the disease is still to be achieved. This is because the cellular and molecular mechanisms
Global Trade Item Number
| SKU | GTIN |
|---|---|
| Z4277-50MG | 04061832787374 |
| Z4277-10MG | 04061837626074 |