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About This Item
UNSPSC Code:
41102404
NACRES:
NB.35
material
aluminum
feature
Holds 96 x 0.2 mL tubes in center plus 10 on size (4 for 1.5ml tubes, 6 for 0.5ml tubes)
packaging
pkg of 1 ea
manufacturer/tradename
Diversified Biotech CHAM-1000
technique(s)
PCR: suitable
size
156x76x25 mm
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General description
Each Cooling Chamber is a solid aluminum block that surrounds inserted tubes to guarantee sustained hot or cold temperatures.
Application
Aluminum heating/cooling block has been used to cool PCR tubes during dilution of DNA fragments and the preparation of the enzyme master mix for in vitro cyclic GMP-AMP synthase (cGAS)reaction.
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Andreas Holleufer et al.
Bio-protocol, 8(20), e3055-e3055 (2018-10-20)
Cyclic GMP-AMP synthase (cGAS) is a pattern recognition receptor (PRR) that senses double stranded DNA (dsDNA) in the cytosol and this leads to the activation of stimulator of interferon genes (STING) via the secondary messenger 2'3'-cyclic GMP-AMP (2'3'-cGAMP). STING then
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