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Merck
CN

40035-U

EPA 521 Nitrosamine Mix

certified reference material, 2000 μg/mL each component in dichloromethane

Synonym(s):

EPA method 521 nitrosamine standard mixture

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About This Item

NACRES:
NA.24
UNSPSC Code:
77101502
Technical Service
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Quality Level

agency

EPA 521

product line

TraceCERT®

grade

certified reference material, TraceCERT®

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 1 × 1 mL

concentration

2000 μg/mL each component in dichloromethane

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

environmental

format

multi-component solution

storage temp.

2-8°C

General description

EPA 521 Nitrosamine Mix is a multi-component solution containing N-nitrosodimethylamine, N-nitrosodibutylamine, N-nitrosodi-n-propylamine, N-nitrosomethylethylamine, N-nitrosodiethylamine, 1-nitrosopyrrolidine, and 1-nitrosopiperidine as certified reference materials (CRMs). The raw materials and solvents used in the preparation of EPA Method 521 Nitrosamine Mix have been screened for identity and purity. The mixture is gravimetrically prepared and quantitatively analyzed by gas chromatography (GC).
US EPA 500 Series methods are analytical methods for identifying and quantifying organic contaminants such as volatile organic compounds (VOCs), pesticides, synthetic organic compounds (SOCs), and trihalomethane disinfection byproducts (THMs) in raw source water, finished drinking water, and drinking water at all stages of treatment.

Application

EPA 521 Nitrosamine Mix may be used as a CRM to quantify N-nitrosamine analytes in fast food products, meat-derived products, tertiary alkanolamine-based carbon dioxide (CO2) capture systems, environmental water samples, and drinking water and drinking water treatment plants(6) by analytical techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany


Analyte

Description

  • N-Nitrosodimethylamine

  • N-Nitrosodibutylamine

  • N-Nitrosodi-n-propylamine

  • N-Nitrosomethylethylamine

  • N-Nitrosodiethylamine

  • 1-Nitrosopyrrolidine

  • 1-Nitrosopiperidine

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

危险化学品

This item has



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Nitrosamines analysis by solid phase extraction (SPE) and subsequent gas chromatography-tandem mass spectrometry (GC-MS/MS) according to GB 5750.10-2023.


Nitrosamine formation in the desorber of tertiary alkanolamine-based carbon dioxide capture systems
Yu K, et al.
Industrial & Engineering Chemistry Research, 55(9), 2604-2614 (2016)
Determination of seven volatile N-nitrosamines in fast food
Al-Kaseem M, et al.
Pharmacology & Pharmacy, 4(08), 611-611 (2013)
Nitrosamines in sucuk: Effects of black pepper, sodium ascorbate and cooking level
Sallan S, et al.
Food Chemistry, 288(08), 341-346 (2019)



Global Trade Item Number

SKUGTIN
40035-U04061831984903