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EPA 521 Nitrosamine Mix

certified reference material, 2000 μg/mL each component in dichloromethane

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NACRES:
NA.24

grade

certified reference material
TraceCERT®

Quality Level

100

Agency

EPA 521

product line

TraceCERT®

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 1 × 1 mL

concentration

2000 μg/mL each component in dichloromethane

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

environmental

format

multi-component solution

storage temp.

2-8°C

Related Categories

General description

EPA 521 Nitrosamine Mix is a multi-component solution containing N-nitrosodimethylamine, N-nitrosodibutylamine, N-nitrosodi-n-propylamine, N-nitrosomethylethylamine, N-nitrosodiethylamine, 1-nitrosopyrrolidine, and 1-nitrosopiperidine as certified reference materials (CRMs). The raw materials and solvents used in the preparation of EPA Method 521 Nitrosamine Mix have been screened for identity and purity. The mixture is gravimetrically prepared and quantitatively analyzed by gas chromatography (GC).
US EPA 500 Series methods are analytical methods for identifying and quantifying organic contaminants such as volatile organic compounds (VOCs), pesticides, synthetic organic compounds (SOCs), and trihalomethane disinfection byproducts (THMs) in raw source water, finished drinking water, and drinking water at all stages of treatment.

Application

EPA 521 Nitrosamine Mix may be used as a CRM to quantify N-nitrosamine analytes in fast food products, meat-derived products, tertiary alkanolamine-based carbon dioxide (CO2) capture systems, environmental water samples, and drinking water and drinking water treatment plants(6) by analytical techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Analyte

Description
    N-Nitrosodimethylamine
    N-Nitrosodibutylamine
    N-Nitrosodi-n-propylamine
    N-Nitrosomethylethylamine
    N-Nitrosodiethylamine
    1-Nitrosopyrrolidine
    1-Nitrosopiperidine

Pictograms

Exclamation markHealth hazard
GHS07,GHS08

Signal Word

Danger

Hazard Statements

H315 - H319 - H336 - H350

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

危险化学品

Certificates of Analysis (COA)

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25G
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Occurrence of N-nitrosamines and their precursors in Spanish drinking water treatment plants and distribution systems
Farre MJ, et al.
Chemosphere, 6(1), 210-220 (2020)
Nitrosamine formation in the desorber of tertiary alkanolamine-based carbon dioxide capture systems
Yu K, et al.
Industrial & Engineering Chemistry Research, 55(9), 2604-2614 (2016)
Fast analysis of multiple haloacetic acids and nitrosamines in recycled and environmental waters using liquid chromatography-mass spectrometry with positive-negative switching and multiple reaction monitoring
Alexandrou LD, et al.
Analytical Methods : Advancing Methods and Applications, 11(30), 3793-3799 (2019)
Determination of seven volatile N-nitrosamines in fast food
Al-Kaseem M, et al.
Pharmacology & Pharmacy, 4(08), 611-611 (2013)
Nitrosamines in sucuk: Effects of black pepper, sodium ascorbate and cooking level
Sallan S, et al.
Food Chemistry, 288(08), 341-346 (2019)

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