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Safety Information

40060

Supelco

N-Nitrosodiphenylamine solution

certified reference material, 5000 μg/mL in methanol

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Synonym(s):
N-Nitroso-N-phenylaniline, Diphenylnitrosamine, Diphenylnitrosoamine
CAS Number:
86-30-6
EC Number:
200-659-6

grade

certified reference material
TraceCERT®

Quality Level

100

Agency

EPA 625,8270,Mar ′90, Dec ′90, Aug ′91 Statement of Work
EPA OLM04 (Statement of Work)

product line

TraceCERT®

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 1 mL

concentration

5000 μg/mL in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

environmental

format

single component solution

storage temp.

2-8°C

InChI

1S/C12H10N2O/c15-13-14(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H

InChI key

UBUCNCOMADRQHX-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Flam. Liq. 2 - STOT SE 1

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F

Flash Point(C)

9.7 °C

Regulatory Information

危险化学品

Certificates of Analysis (COA)

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K E Appel et al.
Archives of toxicology, 60(1-3), 204-208 (1987-01-01)
Nitrosodiphenylamine was tested for induction of DNA single strand breaks in rat hepatocytes and Chinese hamster V 79 cells with the alkaline filter elution assay. While in rat hepatocytes DNA damage could be observed, negative results were obtained in V
A el-Yazigi et al.
Therapeutic drug monitoring, 17(5), 511-515 (1995-10-01)
A rapid and expedient liquid chromatographic method for the analysis of paclitaxel in plasma is described. Paclitaxel and the internal standard (IS, N-nitrosodiphenylamine) were separated on a 10-microns particle, 8 mm x 10 cm C18 cartridge in conjunction with a
The genetic toxicology of N-nitrosodiphenylamine.
D McGregor
Mutation research, 317(3), 195-211 (1994-06-01)
S E Atawodi et al.
European journal of drug metabolism and pharmacokinetics, 15(1), 27-29 (1990-01-01)
Pharmacokinetic investigations into the biliary excretion of N-nitrosodiphenylamine given as an i.p. dose of 50 mg/kg were conducted and results compared in three animal species; rat, guinea pig and rabbit following bile duct cannulation and collection of bile in vitro.
Masayoshi Sawamura et al.
Journal of agricultural and food chemistry, 53(10), 4281-4287 (2005-05-12)
The inhibitory effect of yuzu (Citrus junos Tanaka) essential oil on the formation of N-nitrosodimethylamine (NDMA) in the presence of vegetables (31 species) or saliva was investigated by HPLC. Most vegetable extracts enhanced the formation of NDMA. However, the formation
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