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47889

Methyl Paraben

Name: Methyl Paraben
Brand: SUPELCO

PESTANAL^®, analytical standard

Synonym(s):

Methyl 4-hydroxybenzoate, p-Hydroxybenzoic acid methyl ester, Methyl paraben, NIPAGIN

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About This Item

Linear Formula:

HOC₆H₄CO₂CH₃

CAS Number:

99-76-3

Molecular Weight:

152.15

UNSPSC Code:

12164500

E Number:

E218

PubChem Substance ID:

24871585

EC Number:

202-785-7

Beilstein/REAXYS Number:

509801

MDL number:

MFCD00002352

NACRES:

NA.24

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grade

analytical standard

Quality Level

100

product line

PESTANAL^®

CofA

current certificate can be downloaded

packaging

ampule of 1000 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

125-128 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-30°C

SMILES string

COC(=O)c1ccc(O)cc1

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

InChI key

LXCFILQKKLGQFO-UHFFFAOYSA-N

Gene Information

rat ... Ar(24208)

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Related Categories

Analytical Chemistry

Food & Cosmetic Component Standards

Food Additive Standards

Reference Materials

General description

Methyl Paraben is a stable, non-volatile, methyl ester of p-hydroxybenzoic acid. It can find applications as a broad-spectrum antimicrobial preservative in foods, drugs and cosmetics. It is found to be noncarcinogenic and is highly effective against fungi like molds and yeast as well as bacteria.

Methyl paraben is basically a methyl ester of p-hydroxybenzoic acid. It is non-toxic, and non-carcinogenic in nature. It is a stable, non-volatile compound and finds application as an anti-microbial preservative in foods, drugs and cosmetics. It is readily absorbed through the skin and gastrointestinal tract. Upon hydrolyzation, it is hydrolyzed to p-hydroxybenzoic acid, and the conjugates formed get rapidly excreted in the urine.

Application

Methyl paraben was used a preservative standard in commercial food products, during an experimental investigation, done to study the application of microemulsion electrokinetic chromatography (MEEKC), in detecting food preservatives.

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Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

334.4 °F

flash_point_c

168 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Bisphenol A Exposure Changes the Transcriptomic and Proteomic Dynamics of Human Retinoblastoma Y79 Cells.

Chul-Hong Kim et al.

Genes, 12(2) (2021-03-07)

Bisphenol A (BPA) is a xenoestrogen chemical commonly used to manufacture polycarbonate plastics and epoxy resin and might affect various human organs. However, the cellular effects of BPA on the eyes have not been widely investigated. This study aimed to

Evaluation of the health aspects of methyl paraben: a review of the published literature

Soni.G.M, et al.

Food And Chemical Toxicology, 40, 1335-1373 (2002)

Application of microemulsion electrokinetic chromatography for the detection of preservatives in foods.

Huang H.y

Food Chemistry, 89 (2), 315-322 (2005)

Combined activation of methyl paraben by light irradiation and esterase metabolism toward oxidative DNA damage

Okamoto Y, et al.

Chemical Research in Toxicology, 21, 1594-1599 (2008)

Evaluation of the health aspects of methyl paraben: a review of the published literature.

Soni MG

Food And Chemical Toxicology, 40 (10), 1335-1373 (2002)

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Global Trade Item Number

SKU	GTIN
47889	04061838082541

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