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Merck
CN

48320-U

N-Nitrosodi-n-butylamine solution

certified reference material, 2000 μg/mL in methylene chloride

Synonym(s):

Dibutyl nitrosamine

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
77101502
EC Number:
200-838-9
NACRES:
NA.24
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Product Name

N-Nitrosodi-n-butylamine solution, certified reference material, 2000 μg/mL in methylene chloride

SMILES string

N(N=O)(CCCC)CCCC

InChI key

YGJHZCLPZAZIHH-UHFFFAOYSA-N

InChI

1S/C8H18N2O/c1-3-5-7-10(9-11)8-6-4-2/h3-8H2,1-2H3

grade

certified reference material

CofA

current certificate can be downloaded

packaging

ampule of 1 mL

concentration

2000 μg/mL in methylene chloride

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

environmental

format

single component solution

storage temp.

2-30°C

Quality Level

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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N-nitrosodi-n-butylamine.
Report on carcinogens : carcinogen profiles, 11, III196-III197 (2004-01-01)
Mohamed F Ismail et al.
International journal of biological sciences, 5(4), 377-387 (2009-06-13)
Spirulina platensis (SP) is a filamentous cyanobacterium microalgae with potent dietary phyto-antioxidant, anti-inflammatory and anti-cancerous properties. The present study aimed to investigate the chemopreventive effect of SP against rat liver toxicity and carcinogenesis induced by dibutyl nitrosamine (DBN) precursors, and
N-Nitrosodi-n-butylamine.
Report on carcinogens : carcinogen profiles, 10, 175-176 (2004-08-26)
M Hirose et al.
Carcinogenesis, 12(10), 1773-1776 (1991-10-01)
The effects of butylated hydroxyanisole (BHA) pretreatment on subsequent low dose N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or N,N-dibutylnitrosamine (DBN) treatment on forestomach or esophageal carcinogenesis were investigated in male F344 rats. Groups of animals were pretreated with 2% BHA or basal diet alone
Volatile N-nitrosamines in selected Italian cheeses.
A Dellisanti et al.
Bulletin of environmental contamination and toxicology, 57(1), 16-21 (1996-07-01)

Articles

GC-MS method detects nitrosamines in Valsartan tablets, meeting US FDA guidelines for pharmaceutical quality control.

亚硝胺经证是沙坦家族活性药物成分 (API) 中的一种严重污染物。本文介绍了一种根据美国 FDA 指南测定缬沙坦片中亚硝胺含量的 GC-MS 方法,适用于药品质量控制。

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