64101
L -Citrulline-1,2,3,4,5-13C5
certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
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TraceCERT®
grade
certified reference material, TraceCERT®
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
format
neat
storage temp.
2-8°C
SMILES string
NC(N[13C][13C][13C][13C](N)[13C](O)=O)=O
General description
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to the SI through a primary reference material from an NMI, e.g. NIST, NRC or NMIJ.
Certified content incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com
Citrulline is a non-proteinogenic amino acid produced in the urea cycle and during nitric oxide synthesis, often used as a biomarker of enterocyte (intestinal) mass and function. Testing citrulline can help assess conditions like short bowel syndrome, mucosal injury from chemotherapy or radiation, and some urea-cycle disorders, supporting both clinical evaluation and research. Accurate measurement commonly uses LC–MS/MS, where a stable isotope–labeled citrulline acts as an internal standard to correct for extraction losses, matrix effects, and instrument variability. Because the labeled standard is chemically identical and co-elutes with native citrulline, it enables robust calibration and improves accuracy, precision, and inter-lab comparability. This leads to more reliable decisions based on citrulline levels.
Discover our portfolio of amino acid reference materals.
Certified content incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com
Citrulline is a non-proteinogenic amino acid produced in the urea cycle and during nitric oxide synthesis, often used as a biomarker of enterocyte (intestinal) mass and function. Testing citrulline can help assess conditions like short bowel syndrome, mucosal injury from chemotherapy or radiation, and some urea-cycle disorders, supporting both clinical evaluation and research. Accurate measurement commonly uses LC–MS/MS, where a stable isotope–labeled citrulline acts as an internal standard to correct for extraction losses, matrix effects, and instrument variability. Because the labeled standard is chemically identical and co-elutes with native citrulline, it enables robust calibration and improves accuracy, precision, and inter-lab comparability. This leads to more reliable decisions based on citrulline levels.
Discover our portfolio of amino acid reference materals.
Legal Information
TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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