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Merck
CN

68102

Supelco

N-Nitrosopiperidine

analytical standard

Synonym(s):

1-Nitrosopiperidine, NPIP

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About This Item

Empirical Formula (Hill Notation):
C5H10N2O
CAS Number:
100-75-4
Molecular Weight:
114.15
MDL number:
MFCD00023652
UNSPSC Code:
41116105
NACRES:
NA.24

Key Documents

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grade

analytical standard

Quality Level

100

Assay

≥98%

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

density

1.06 g/mL (lit.)

format

neat

storage temp.

2-8°C

SMILES string

O=NN1CCCCC1

InChI key

UWSDONTXWQOZFN-UHFFFAOYSA-N

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General description

Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosopiperidine is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.

Application

N-Nitrosopiperidine may be used as an analytical reference standard for the determination of volatile nitrosamines in meat samples using reversed-phase high-performance liquid chromatography (RP-HPLC).

Biochem/physiol Actions

Carcinogen that induces benign and malignant tumors of the respiratory tract, stomach and esophagus in rodents; potent nasal carcinogen in rats.

Analysis Note

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301,H351

Hazard Classifications

Acute Tox. 3 Oral - Carc. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM8791
BCCJ6031

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A rapid, validated RP-HPLC method for the determination of seven volatile N-Nitrosamines in meat
Al-Kaseem, et al.
Asian Journal of Pharmacy and Pharmacology, 5, 298-308 (2014)

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