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Merck
CN

77558

Pipecolinic acid

new

analytical standard

Synonym(s):

(±)-Piperidine-2-carboxylic acid, 2-Piperidinecarboxylic acid, Homoproline, Pipecolic acid free base

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About This Item

Empirical Formula (Hill Notation):
C6H11NO2
CAS Number:
Molecular Weight:
129.16
Beilstein:
81095
MDL number:
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grade

analytical standard

Quality Level

technique(s)

HPLC: suitable
LC/MS: suitable
liquid chromatography (LC): suitable
mass spectrometry (MS): suitable

mp

282 °C (dec.) (lit.)

application(s)

clinical
food and beverages

format

neat

SMILES string

OC(=O)C1CCCCN1

InChI

1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)

InChI key

HXEACLLIILLPRG-UHFFFAOYSA-N

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General description

Pipecolic acid (piperidine-2-carboxylic acid) is a non-proteinogenic cyclic amino acid formed during lysine catabolism and further processed in peroxisomes. Elevated levels are a useful biomarker for peroxisomal biogenesis disorders and can also appear in pyridoxine-dependent epilepsy and certain liver-related conditions. Testing pipecolic acid in serum or urine—typically by LC–MS/MS—supports differential diagnosis and monitoring.

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