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Merck
CN

Y0002371

Mirabegron

CRS, European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Mirabegron, 2-(2-Amino-1,3-thiazol-4-yl)-N-[4-[2-[((2R)-2-hydroxy-2-phenylethyl)amino]ethyl]phenyl]acetamide, 2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide, YM 178, YM178(R)-Mirabegron

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About This Item

Empirical Formula (Hill Notation):
C21H24N4O2S
CAS Number:
223673-61-8
Molecular Weight:
396.51
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
MFCD11100356

Key Documents

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Product Name

Mirabegron, CRS, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C21H24N4O2S/c22-21-25-18(14-28-21)12-20(27)24-17-8-6-15(7-9-17)10-11-23-13-19(26)16-4-2-1-3-5-16/h1-9,14,19,23,26H,10-13H2,(H2,22,25)(H,24,27)/t19-/m0/s1

SMILES string

O[C@@H](CNCCC1=CC=C(NC(CC2=CSC(N)=N2)=O)C=C1)C3=CC=CC=C3

InChI key

PBAPPPCECJKMCM-IBGZPJMESA-N

grade

pharmaceutical primary standard

API family

mirabegron

manufacturer/tradename

EDQM

application(s)

pharmaceutical

storage temp.

2-8°C

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Application

Mirabegron EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Mirabegron is a potent and selective β3-adrenoceptor agonist that activates the β3 adrenergic receptor in the detrusor muscle in the bladder leading to muscle relaxation and an increase in bladder capacity.
potent and selective β3-adrenoceptor agonist

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

Unit quantity: 120mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H361d

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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