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Merck
CN

1012553

USP

Albendazole

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Methyl 5-(propylthio)-2-benzimidazolecarbamate

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About This Item

Empirical Formula (Hill Notation):
C12H15N3O2S
CAS Number:
Molecular Weight:
265.33
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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grade

pharmaceutical primary standard

API family

albendazole

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChI key

HXHWSAZORRCQMX-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Albendazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Albendazole Oral Suspension
  • Albendazole Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Health hazardEnvironment

signalword

Warning

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral

target_organs

Adrenal gland,Blood,male reproductive organs,spleen

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

农药列管产品

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Julia Critchley et al.
Tropical medicine & international health : TM & IH, 10(9), 818-825 (2005-09-02)
The Global Programme to Eliminate Lymphatic Filariasis recommends albendazole in combination with other antifilarial drugs. This systematic review examines albendazole in treatment and control of lymphatic filariasis. DATASOURCES: The Cochrane Controlled Trials Register, MEDLINE and EMBASE to April 2005; contacting
Uwe Gross
Parasitology research, 90 Supp 1, S14-S18 (2003-06-18)
Microsporidia are parasitic fungi that can infect not only arthropods and fish, but also mammals including humans. This article describes the biology of these primitive fungi and gives an overview on recent developments in therapy. Encephalitozoonspp. and the species Enterocytozoon
Matthew E Falagas et al.
The American journal of the medical sciences, 334(3), 171-179 (2007-09-18)
Albendazole has been used in various ways in the treatment of cystic echinococcosis (CE). We reviewed the available evidence regarding the role of albendazole for the treatment of patients with CE. The available comparative clinical trials (randomized or not) that
M E Oxberry et al.
Journal of veterinary pharmacology and therapeutics, 23(3), 113-120 (2000-12-08)
Trophozoites of the protozoan parasite Giardia duodenalis were exposed to various albendazole concentrations for 4 h, washed, fixed and incubated with antibodies raised against albendazole and its two major metabolites albendazole sulphoxide and albendazole sulphone. Tubulin antibodies were also used.
John Horton
Current opinion in infectious diseases, 15(6), 599-608 (2003-06-25)
It is over 25 years ago since the original animal research was conducted into albendazole. This review highlights some important steps in fundamental research and the management of helminth disease that have occurred in the past year, appearing in the

Global Trade Item Number

SKUGTIN
1012553-200MG04061838667212

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