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Merck
CN

1012553

USP

Albendazole

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Methyl 5-(propylthio)-2-benzimidazolecarbamate

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About This Item

Empirical Formula (Hill Notation):
C12H15N3O2S
CAS Number:
54965-21-8
Molecular Weight:
265.33
NACRES:
NA.24
PubChem Substance ID:
329748945
UNSPSC Code:
41116107
MDL number:
MFCD00083232

Key Documents

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Product Name

Albendazole, United States Pharmacopeia (USP) Reference Standard

InChI key

HXHWSAZORRCQMX-UHFFFAOYSA-N

SMILES string

CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

grade

pharmaceutical primary standard

API family

albendazole

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Albendazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Albendazole Oral Suspension
  • Albendazole Tablets

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Health hazardEnvironment
GHS08,GHS09

signalword

Warning

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral

target_organs

Adrenal gland,Blood,male reproductive organs,spleen

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

农药列管产品
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Julia Critchley et al.
Tropical medicine & international health : TM & IH, 10(9), 818-825 (2005-09-02)
The Global Programme to Eliminate Lymphatic Filariasis recommends albendazole in combination with other antifilarial drugs. This systematic review examines albendazole in treatment and control of lymphatic filariasis. DATASOURCES: The Cochrane Controlled Trials Register, MEDLINE and EMBASE to April 2005; contacting
Marlieke E A de Kraker et al.
Tropical medicine & international health : TM & IH, 11(5), 718-728 (2006-04-28)
To determine the efficacies of combinations of ivermectin or diethylcarbamazine and albendazole, which are recommended for use in mass treatment programmes against lymphatic filariasis. Review of published trends in microfilarial (mf) intensities after treatment with these combination therapies. By fitting
J Horton
Annals of tropical medicine and parasitology, 103 Suppl 1, S33-S40 (2009-11-11)
The history of the development of ivermectin and diethylcarbamazine for the treatment of human filarial infections is relatively well known and documented. The story of how albendazole became involved in the global elimination programmes is, however, less well known. This
Uwe Gross
Parasitology research, 90 Supp 1, S14-S18 (2003-06-18)
Microsporidia are parasitic fungi that can infect not only arthropods and fish, but also mammals including humans. This article describes the biology of these primitive fungi and gives an overview on recent developments in therapy. Encephalitozoonspp. and the species Enterocytozoon
John Horton
Current opinion in infectious diseases, 15(6), 599-608 (2003-06-25)
It is over 25 years ago since the original animal research was conducted into albendazole. This review highlights some important steps in fundamental research and the management of helminth disease that have occurred in the past year, appearing in the
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