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USP

Arginine hydrochloride

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
L-Arginine monohydrochloride, L-(+)-Arginine monohydrochloride, (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride, (S)-(+)-Arginine hydrochloride
Empirical Formula (Hill Notation):
C6H14N4O2 · HCl
CAS Number:
Molecular Weight:
210.66
Beilstein:
3631658
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

arginine

form

powder

manufacturer/tradename

USP

solubility

alcohol: slightly soluble
ether: insoluble
water: freely soluble

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1

InChI key

KWTQSFXGGICVPE-WCCKRBBISA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Arginine hydrochloride USP reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare standard and system suitability solution during the assay, impurity analysis, strength analysis and identification by using liquid chromatography coupled with UV detector according to the given below monographs of United States Pharmacopeia (USP): 
  • Arginine Hydrochloride Compounded Oral Solution
  • Arginine Tablets
  • Arginine Capsules

Biochem/physiol Actions

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Arginine Capsules
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 36(1) (2013)
Arginine Hydrochloride Compounded Oral Solution
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(5), 372-372 (2020)
Arginine Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 48(3), 1982-1982 (2013)

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