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Merck
CN

1118361

USP

Chloroquine Related Compound E

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

N4-(5-Chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine oxalate

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About This Item

Empirical Formula (Hill Notation):
C20H28ClN3O4
CAS Number:
5428-61-5
Molecular Weight:
409.91
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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SMILES string

Clc1c2c(nccc2NC(CCCN(CC)CC)C)ccc1

InChI

1S/C18H26ClN3/c1-4-22(5-2)13-7-8-14(3)21-17-11-12-20-16-10-6-9-15(19)18(16)17/h6,9-12,14H,4-5,7-8,13H2,1-3H3,(H,20,21)

InChI key

CHDBGFBFAXJWRC-UHFFFAOYSA-N

biological source

synthetic

grade

pharmaceutical primary standard

agency

USP

API family

chloroquine

form

solid

packaging

pkg of 10 mg

manufacturer/tradename

USP

storage condition

protect from light

color

white

application(s)

pharmaceutical (small molecule)

format

neat

Related Categories

General description

Chloroquine Related Compound E is an impurity of chloroquine, which is a 9-aminoquinoline drug that effectively inhibits viral infections in humans.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Chloroquine Related Compound E can be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography (LC) technique
Also, for use with USP monograph such as Chloroquine Phosphate.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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Chloroquine Phosphate
Pharmacopeia, US
United States Pharmacopeia, 39(3), 959-959 (2020)
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
Vincent MJ, et al.
Virology Journal, 2(1), 1-10 (2005)

Protocols

Chloroquine Phosphate HPLC Assay & Impurity Profiling

Chloroquine Phosphate HPLC Assay meets system suitability criteria with good resolution, reproducibility, and sensitivity.

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