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USP

Cimetidine

Name: Cimetidine
Brand: USP

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):

SKF-92334

Empirical Formula (Hill Notation):

C₁₀H₁₆N₆S

CAS Number:

51481-61-9

Molecular Weight:

252.34

MDL number:

MFCD00133296

PubChem Substance ID:

329749396

NACRES:

NA.24

grade

pharmaceutical primary standard

API family

cimetidine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CN\C(NC#N)=N\CCSCc1nc[nH]c1C

InChI

1S/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)

InChI key

AQIXAKUUQRKLND-UHFFFAOYSA-N

Gene Information

human ... HRH2(3274)

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Analytical Reference Standards

Sigma-Aldrich

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cimetidine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

related product

Product No.

Description

Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Automation of a high risk medication regime algorithm in a home health care population.

Catherine H Olson et al.

Journal of biomedical informatics, 51, 60-71 (2014-04-17)

Create an automated algorithm for predicting elderly patients' medication-related risks for readmission and validate it by comparing results with a manual analysis of the same patient population. Outcome and Assessment Information Set (OASIS) and medication data were reused from a

Cimetidine attenuates vinorelbine-induced phlebitis in mice by militating E-selectin expression.

Zhuo Wang et al.

Cancer chemotherapy and pharmacology, 74(2), 239-247 (2014-06-01)

We investigated E-selectin expression in mice and rabbits with vinorelbine-induced phlebitis and the effect of cimetidine. To find the relationship between E-selectin expression and vinorelbine-induced phlebitis. Mouse and rabbit model of vinorelbine-induced phlebitis was established by intravenous infusion of vinorelbine.

Histamine upregulates Nav1.8 expression in primary afferent neurons via H2 receptors: involvement in neuropathic pain.

Jia-Xing Yue et al.

CNS neuroscience & therapeutics, 20(10), 883-892 (2014-07-06)

The upregulation of Nav1.8 in primary afferents plays a critical role in the development and persistence of neuropathic pain. The mechanisms underlying the upregulation are not fully understood. The present study aims to investigate the regulatory effect of histamine on

Validation of phenol red versus gravimetric method for water reabsorption correction and study of gender differences in Doluisio's absorption technique.

Fatmanur Tuğcu-Demiröz et al.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 62, 105-110 (2014-06-03)

The aim of the present study was to develop a method for water flux reabsorption measurement in Doluisio's Perfusion Technique based on the use of phenol red as a non-absorbable marker and to validate it by comparison with gravimetric procedure.

Effects of renal impairment on the pharmacokinetics of morinidazole: uptake transporter-mediated renal clearance of the conjugated metabolites.

Kan Zhong et al.

Antimicrobial agents and chemotherapy, 58(7), 4153-4161 (2014-05-14)

Morinidazole is a novel 5-nitroimidazole antimicrobial drug that undergoes extensive metabolism in humans via N(+)-glucuronidation (N(+)-glucuronide of S-morinidazole [M8-1] and N(+)-glucuronide of R-morinidazole [M8-2]) and sulfation (sulfate conjugate of morinidazole [M7]). Our objectives were to assess the effects of renal

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