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1140430

USP

Clopidogrel bisulfate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

(S)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogensulfate

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About This Item

Empirical Formula (Hill Notation):
C16H16ClNO2S · H2SO4
CAS Number:
120202-66-6
Molecular Weight:
419.90
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329749435
MDL number:
MFCD00876395
Beilstein/REAXYS Number:
9967887
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grade

pharmaceutical primary standard

API family

clopidogrel

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

OS(O)(=O)=O.COC(=O)[C@@H](N1CCc2sccc2C1)c3ccccc3Cl

InChI

1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m0./s1

InChI key

FDEODCTUSIWGLK-RSAXXLAASA-N

Gene Information

human ... P2RY12(64805)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Clopidogrel bisulfate USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Clopidogrel Bisulfate
  • Clopidogrel Tablets
  • Clopidogrel Compounded Oral Suspension

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Disclaimer

Sales restrictions may apply.

pictograms

CorrosionEnvironment
GHS05,GHS09

signalword

Danger

hcodes

H314,H411

Hazard Classifications

Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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Kailas S Khomane et al.
Journal of pharmaceutical sciences, 101(7), 2408-2416 (2012-04-11)
Being a density violator, clopidogrel bisulfate (CLP) polymorphic system (forms I and II) allows us to study individually the impact of molecular packing (true density) and thermodynamic properties such as heat of fusion on the compaction behavior. These two polymorphs
Clopidogrel Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 33(1), 1111-1111 (2020)
Clopidogrel Compounded Oral Suspension
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(5), 1111-1111 (2014)
Clopidogrel Bisulfate
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 38(1), 1109-1109 (2020)
Kyoung-Woo Seo et al.
Clinical therapeutics, 36(11), 1588-1594 (2014-09-15)
Platelet-function suppression with antiplatelet therapy is effective in preventing and treating cardiovascular disease. Clopidogrel is a thienopyridine derivative that blocks platelet activation by adenosine diphosphate receptor binding. This study demonstrates the effects of generic clopidogrel bisulfate in comparison to branded
View All Related Papers

Global Trade Item Number

SKUGTIN
1140430-125MG04061838701664

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