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About This Item
Empirical Formula (Hill Notation):
C20H18O5
CAS Number:
Molecular Weight:
338.35
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
Product Name
Desmethoxycurcumin, United States Pharmacopeia (USP) Reference Standard
SMILES string
O(C)c1c(ccc(c1)\C=C\C(=O)CC(=O)\C=C\c2ccc(cc2)O)O
InChI
1S/C20H18O5/c1-25-20-12-15(6-11-19(20)24)5-10-18(23)13-17(22)9-4-14-2-7-16(21)8-3-14/h2-12,21,24H,13H2,1H3/b9-4+,10-5+
InChI key
HJTVQHVGMGKONQ-LUZURFALSA-N
grade
pharmaceutical primary standard
API family
curcumin
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Desmethoxycurcumin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Curcuminoids Tablets
- Curcuminoids
- Powdered Turmeric Extract
- Powdered Turmeric
- Turmeric
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Yan Shen et al.
Journal of pharmaceutical and biomedical analysis, 81-82, 146-150 (2013-05-08)
A sensitive and efficient method based on pressurized liquid extraction (PLE) followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed for simultaneous identification and quantification of three Curcuminoids in Curcuma wenyujin Y.H.chen et C.Ling., a well known traditional Chinese medicinal
Yanyu Xiao et al.
Journal of agricultural and food chemistry, 61(15), 3654-3660 (2013-03-05)
Curcuminoid, a dietary polyphenolic compound, has poor water solubility and low bioavailability following oral administration. The aim of this study was to develop a formulation of curcuminoid-loaded microemulsion (Cur-ME) to improve its oral bioavailability. The optimized Cur-ME formulation was prepared
Ming-Jyh Sheu et al.
Molecular nutrition & food research, 57(9), 1586-1597 (2013-03-23)
Curcumin has been shown to affect platelet-derived growth factor (PDGF)- and tumor necrosis factor (TNF)-α-elicited vascular smooth muscle cell (VSMC) migration and inhibit neointima formation following vascular injury. However, whether two other curcuminoids isolated from Curcuma longa, demethoxycurcumin (DMC) and
Jian-Lan Jiang et al.
Chemical biology & drug design, 81(5), 650-657 (2013-01-29)
Traditionally, active compounds were discovered from natural product extracts by bioassay-guided fractionation, which was with high cost and low efficiency. A well-trained support vector regression model based on mean impact value was used to identify lead active compounds on inhibiting
Ying-Bo Li et al.
International journal of molecular medicine, 27(2), 205-211 (2010-12-08)
Curcuminoids are the major active components extracted from Curcuma longa and are well known for their antioxidant effects. Previous studies have reported that the antioxidant properties of curcuminoids are mainly attributed to their free radical scavenging abilities. However, whether there
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