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About This Item
Product Name
Dibutyl sebacate, United States Pharmacopeia (USP) Reference Standard
InChI
1S/C18H34O4/c1-3-5-15-21-17(19)13-11-9-7-8-10-12-14-18(20)22-16-6-4-2/h3-16H2,1-2H3
SMILES string
CCCCOC(=O)CCCCCCCCC(=O)OCCCC
InChI key
PYGXAGIECVVIOZ-UHFFFAOYSA-N
grade
pharmaceutical primary standard
form
liquid
manufacturer/tradename
USP
refractive index
n20/D 1.441 (lit.)
bp
178-179 °C/3 mmHg (lit.)
density
0.936 g/mL at 25 °C (lit.)
application(s)
USP Biologics
pharmaceutical (small molecule)
format
neat
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Analysis Note
Application
- Ethylcellulose Dispersion Type B
General description
Dibutyl sebacate is another plasticizer utilized in biologics, primarily in the development of flexible, durable formulations. It is particularly important in the formulation of controlled-release systems, where its inclusion helps maintain the integrity of the polymer matrix over extended periods. Dibutyl sebacate is often used in combination with other excipients to enhance the solubility and stability of active ingredients in biologic formulations.
The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.
For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
352.4 °F - closed cup
flash_point_c
178 °C - closed cup
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