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1187091

USP

Dibutyl sebacate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Decanedioic acid dibutyl ester, Sebacic acid dibutyl ester

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About This Item

Linear Formula:
[-(CH2)4CO2(CH2)3CH3]2
CAS Number:
109-43-3
Molecular Weight:
314.46
Beilstein:
1798308
MDL number:
MFCD00027218
UNSPSC Code:
41116107
PubChem Substance ID:
329749371
NACRES:
NA.24

grade

pharmaceutical primary standard

form

liquid

manufacturer/tradename

USP

refractive index

n20/D 1.441 (lit.)

bp

178-179 °C/3 mmHg (lit.)

density

0.936 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CCCCOC(=O)CCCCCCCCC(=O)OCCCC

InChI

1S/C18H34O4/c1-3-5-15-21-17(19)13-11-9-7-8-10-12-14-18(20)22-16-6-4-2/h3-16H2,1-2H3

InChI key

PYGXAGIECVVIOZ-UHFFFAOYSA-N

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General description

Dibutyl sebacate is another plasticizer utilized in biologics, primarily in the development of flexible, durable formulations. It is particularly important in the formulation of controlled-release systems, where its inclusion helps maintain the integrity of the polymer matrix over extended periods. Dibutyl sebacate is often used in combination with other excipients to enhance the solubility and stability of active ingredients in biologic formulations.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dibutyl sebacate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Ethylcellulose Dispersion Type B

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

This product is part of USP Biologics Program.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pha
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

352.4 °F - closed cup

Flash Point(C)

178 °C - closed cup

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