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1254508

USP

Estriol

Name: Estriol
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

1,3,5(10)-Estratriene-3,16α,17β-triol, 16α-Hydroxyestradiol, 3,16α,17β-Trihydroxy-1,3,5(10)-estratriene

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₂₄O₃

CAS Number:

50-27-1

Molecular Weight:

288.38

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329749756

MDL number:

MFCD00003691

Beilstein/REAXYS Number:

2508172

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grade

pharmaceutical primary standard

API family

estriol

manufacturer/tradename

USP

mp

280-282 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1C[C@@H](O)[C@@H]2O

InChI

1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1

InChI key

PROQIPRRNZUXQM-ZXXIGWHRSA-N

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Related Categories

Pharmacopeia & Metrological Institute Standards

Analytical Reference Materials for Pharma QC

General description

Estriol is found to be a major estrogen in pregnant women. It originates in the placenta from the estrogen precursors, made by the fetal adrenal gland and liver. Estriol levels are directly related to the delivery of the fetus and serve as an index of the fetal well-being.

Application

Estriol USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Estriol Compounded Vaginal Cream

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

pictograms

GHS08

signalword

Danger

hcodes

H351,H360FD,H362

pcodes

P202 - P260 - P263 - P264 - P280 - P308 + P313

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Regulatory Information

涉药品监管产品

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Determination of 17 $\beta$-estradiol in pharmaceutical preparation by UV spectrophotometry and high performance liquid chromatography methods

Yilmaz B and Kadioglu Y

Arabian Journal of Chemistry, 10(3), S1422-S1428 (2017)

Development and validation of a liquid chromatographic method for the simultaneous determination of estradiol, estriol, estrone, and progesterone in pharmaceutical preparations

Wilson P

Journal of AOAC (Association of Official Analytical Chemists) International, 92(3), 846-854 (2009)

"Handbook of Poylmer-Liquid Interaction Parameters and Solubility Parameters ", 27(22), 4431-4438 (2012)

Simultaneous determination of natural and synthetic estrogens by EKC using a novel microemulsion

Tripodi V, et al.

Electrophoresis, 27(22), 4431-4438 (2006)

Global Trade Item Number

SKU	GTIN
1254508-100MG	04061838723581

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