1295800
USP
Glycine
United States Pharmacopeia (USP) Reference Standard
Synonym(s):
Aminoacetic acid, Aminoethanoic acid, Glycocoll
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About This Item
Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
Beilstein:
635782
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
grade
pharmaceutical primary standard
API family
glycine
manufacturer/tradename
USP
pH
4(0.2 molar aqueous solution)
pKa (25 °C)
(1) 2.35, (2) 9.60
2.35
mp
240 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
NCC(O)=O
InChI
1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChI key
DHMQDGOQFOQNFH-UHFFFAOYSA-N
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Glycine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Glycine Irrigation
- Theophylline Sodium Glycinate
- Glycyl-l-tyrosine
- Glycyl-l-glutamine
- Pyrroloquinoline Quinone Disodium
Biochem/physiol Actions
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 1
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Glycine
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 38(6), 6082-6082 (2018)
Glycyl-l-tyrosine
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(4), 5059-5059 (2020)
Theophylline Sodium Glycinate
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 4333-4333 (2020)
Alexander Carvajal-González et al.
Brain : a journal of neurology, 137(Pt 8), 2178-2192 (2014-06-22)
The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.
Pierre Chue
Current pharmaceutical design, 19(7), 1311-1320 (2012-12-01)
Primary negative symptoms (affective flattening or blunting, alogia, avolition) are prominent in approximately 20% of individuals suffering from schizophrenia. These symptoms are particularly associated with impaired functional outcome and poor prognosis. This is in part due to the lack of
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