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USP

Glycine

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
Aminoacetic acid, Aminoethanoic acid, Glycocoll
Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
Beilstein:
635782
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

glycine

manufacturer/tradename

USP

pH

4(0.2 molar aqueous solution)

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Glycine USP reference standard for specified quality tests and assay use only.

Also used to prepare standard and system suitability solutions for the assay and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Glycine
  • Theophylline Sodium Glycinate
  • Glycyl-l-tyrosine

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1


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Glycine
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 38(6), 6082-6082 (2018)
Theophylline Sodium Glycinate
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 4333-4333 (2020)
Glycyl-l-tyrosine
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(4), 5059-5059 (2020)
Pierre Chue
Current pharmaceutical design, 19(7), 1311-1320 (2012-12-01)
Primary negative symptoms (affective flattening or blunting, alogia, avolition) are prominent in approximately 20% of individuals suffering from schizophrenia. These symptoms are particularly associated with impaired functional outcome and poor prognosis. This is in part due to the lack of
Alexander Carvajal-González et al.
Brain : a journal of neurology, 137(Pt 8), 2178-2192 (2014-06-22)
The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.

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