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About This Item
Empirical Formula (Hill Notation):
C7H8ClN3O4S2
CAS Number:
Molecular Weight:
297.74
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13)
SMILES string
NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl
InChI key
JZUFKLXOESDKRF-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
hydrochlorothiazide
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
human ... SLC12A3(6559)
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Hydrochlorothiazide USP reference standard for use in specified quality tests and assays.
Also used to prepare standard, standard stock, system suitability, Hydrochlorothiazide standard solutions for assay, performance, and impurity analysis according to given below monographs of the United States Pharmacopeia (USP):
Also used to prepare standard, standard stock, system suitability, Hydrochlorothiazide standard solutions for assay, performance, and impurity analysis according to given below monographs of the United States Pharmacopeia (USP):
- Hydrochlorothiazide Capsules
- Amiloride Hydrochloride and Hydrochlorothiazide Tablets
- Captopril and Hydrochlorothiazide Tablets
Biochem/physiol Actions
Carbonic anhydrase inhibitor
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Carc. 2
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
监管及禁止进口产品
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Captopril and Hydrochlorothiazide Tablets
United States Pharmacopeia, 43(4), 737-737 (2019)
Amiloride Hydrochloride and Hydrochlorothiazide Tablets
United States Pharmacopeia, 44(3), 224-224 (2019)
Hydrochlorothiazide Capsules
United States Pharmacopeia, 44(1), 2219-2219 (2019)
Franz H Messerli et al.
The American journal of medicine, 124(10), 896-899 (2011-10-04)
Hydrochlorothiazide (HCTZ) has become by far the most commonly prescribed antihypertensive drug in the US. In 2008, 47.8 million prescriptions were written for HCTZ alone and 87.1 million prescriptions for HCTZ combinations. However, there is no evidence that HCTZ in
Soham Rej et al.
Drugs & aging, 31(12), 911-916 (2014-10-22)
Little is known about how lithium should be dosed to achieve therapeutic but safe serum concentrations in older adults. In this paper, we investigate how the lithium dose-concentration ratio changes across the lifespan. This was a cross-sectional analysis of 63
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