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1356665

USP

Ketorolac Tromethamine

Name: Ketorolac Tromethamine
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Ketorolac tris salt, (±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid tris salt, Toradol

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₃NO₃ · C₄H₁₁NO₃

CAS Number:

74103-07-4

Molecular Weight:

376.40

NACRES:

NA.24

PubChem Substance ID:

329750219

UNSPSC Code:

41116107

MDL number:

MFCD00887595

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grade

pharmaceutical primary standard

API family

ketorolac

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

NC(CO)(CO)CO.OC(=O)C1CCn2c1ccc2C(=O)c3ccccc3

InChI

1S/C15H13NO3.C4H11NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13;5-4(1-6,2-7)3-8/h1-7,11H,8-9H2,(H,18,19);6-8H,1-3,5H2

InChI key

BWHLPLXXIDYSNW-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742), PTGS2(5743)

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Related Categories

Analytical Reference Materials for Pharma QC

Pharmacopeia & Metrological Institute Standards

Reference Materials

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ketorolac Tromethamine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

pictograms

GHS06

signalword

Danger

hcodes

H301,H315,H319,H335

pcodes

P261 - P264 - P270 - P301 + P310 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Intra-articular tibiofemoral injection of a nonsteroidal anti-inflammatory drug has no detrimental effects on joint mechanics in a rat model.

Corinne N Riggin et al.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 32(11), 1512-1519 (2014-07-02)

Administration of intra-articular medications, including corticosteroids and analgesics, is common clinical practice for knee pathology and dysfunction. Non-steroidal anti-inflammatory drugs (NSAIDs) are another category of medication commonly prescribed for their analgesic and anti-inflammatory properties. Recent studies demonstrated the efficacy of

Changes in sexual function after medical or surgical termination of pregnancy.

Matteo Morotti et al.

The journal of sexual medicine, 11(6), 1495-1504 (2014-03-19)

Voluntary termination of pregnancy (TOP) is a social issue; however, even if it is one of the most common procedures performed in the world, few studies evaluated sexual function changes after medical or surgical TOP. The aim of this study

Optimization of combinational intranasal drug delivery system for the management of migraine by using statistical design.

Animesh Kumar et al.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 70, 140-151 (2015-02-14)

Migraine is a chronic disorder characterized by significant headache and various associated symptoms which worsen with exertion. Zolmitriptan approved for use in the acute treatment of migraine and related vascular headaches but are limited by high pain recurrence due to

Topical NSAIDs effect on corneal sensitivity.

Daniel D Singer et al.

Cornea, 34(5), 541-543 (2015-04-01)

Topical nonsteroidal antiinflammatory drugs (NSAIDs) are administered topically for a variety of ophthalmologic conditions. Brand diclofenac and brand ketorolac were previously shown to have topical anesthetic effects in addition to analgesic effects. Using the same method, we measured similar anesthetic

Prophylactic use of ketorolac tromethamine in cataract surgery: a randomized trial.

Flavia G Ticly et al.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 30(6), 495-501 (2014-04-17)

To determine the efficacy of topical ketorolac tromethamine in preventing cystoid macular edema (CME) after uncomplicated cataract surgery. This single-center, prospective, double-masked, randomized clinical trial consisted of 81 patients who were scheduled for cataract surgery. Patients were randomized to receive

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Global Trade Item Number

SKU	GTIN
1356665-200MG	04061838730817

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