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1370611

USP

Lovastatin Related Compound A

Name: Lovastatin Related Compound A
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Dihydrolovastatin

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About This Item

Empirical Formula (Hill Notation):

C₂₄H₃₈O₅

CAS Number:

77517-29-4

Molecular Weight:

406.56

MDL number:

MFCD26142879

UNSPSC Code:

41116107

NACRES:

NA.24

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grade

pharmaceutical primary standard

API family

lovastatin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O1[C@@H](C[C@H](CC1=O)O)CC[C@@H]2[C@H]3[C@H](C[C@@H](C[C@@H]3OC(=O)[C@H](CC)C)C)C=C[C@@H]2C

InChI

1S/C24H38O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,14-21,23,25H,5,8-13H2,1-4H3/t14-,15-,16-,17-,18+,19+,20-,21-,23+/m0/s1

InChI key

IFIFFBWHLKGTMO-LDIGTXGYSA-N

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Analytical Reference Materials for Pharma QC

Pharmacopeia & Metrological Institute Standards

Reference Materials

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Dihydromevinolin, a potent hypocholesterolemic metabolite produced by Aspergillus terreus.

G Albers-Schönberg et al.

The Journal of antibiotics, 34(5), 507-512 (1981-05-01)

A new, potent hypocholesterolemic agent is produced by cultures of Aspergillus terreus. The isolation of the compound and its characterization as 4a,5-dihydromevinolin containing a trans-fused octahydro-naphthalene system are described. Comparative data for dihydromevinolin and mevinolin in three biological assays are

Total synthesis and biological evaluation of structural analogues of compactin and dihydromevinolin.

C H Heathcock et al.

Journal of medicinal chemistry, 30(10), 1858-1873 (1987-10-01)

The full experimental details for the total synthesis of (+)-compactin and 19 structural analogues are reported. We have evaluated three classes of analogues as inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase: (1) functional and stereoisomeric analogues that possess the full carbon skeleton

Global Trade Item Number

SKU	GTIN
1370611-20MG	04061833860342

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