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Merck
CN

1379081

USP

Calcium D,L-5-methyltetrahydrofolate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid

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About This Item

Empirical Formula (Hill Notation):
C20H23CaN7O6
CAS Number:
26560-38-3
Molecular Weight:
497.52
MDL number:
MFCD28145139
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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SMILES string

[Ca+2].N1(C(CNc3nc(nc(c31)[O-])N)CNc2ccc(cc2)C(=O)N[C@@H](CCC(=O)[O-])C(=O)O)C

InChI

1S/C20H25N7O6.Ca/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29;/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31);/q;+2/p-2/t12?,13-;/m0./s1

InChI key

VWBBRFHSPXRJQD-ZEDZUCNESA-L

grade

pharmaceutical primary standard

API family

calcium d,l-5-methyltetrahydrofolate

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This USP reference standard is intended for use in specified quality tests and assays.
Also used to prepare standard and system suitability solutions in the strength and impurity analysis by HPLC according to the following United States Pharmacopeia (USP) monographs:
  • Calcium l-5-Methyltetrahydrofolate Tablets
  • Calcium l-5-Methyltetrahydrofolate Capsules

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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Calcium l-5-Methyltetrahydrofolate Capsules
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3), 4841-4841 (2016)
Calcium l-5-Methyltetrahydrofolate Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3), 4842-4842 (2016)

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