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Merck
CN

1379401

USP

Meloxicam

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

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About This Item

Empirical Formula (Hill Notation):
C14H13N3O4S2
CAS Number:
71125-38-7
Molecular Weight:
351.40
MDL number:
MFCD00868752
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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grade

pharmaceutical primary standard

API family

meloxicam

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,19H,1-2H3,(H,15,16)/b13-11+

InChI key

DWMREKMVXIFPFM-ACCUITESSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Meloxicam USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Meloxicam Oral Suspension
  • Meloxicam Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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[The new nonsteroidal anti-inflammatory preparation meloxicam in the treatment of rheumatoid arthritis].
E I Grishina
Likars'ka sprava, (2)(2), 19-25 (1997-03-01)
Mansoor Ahmed et al.
Expert opinion on drug metabolism & toxicology, 1(4), 739-751 (2006-07-26)
Rheumatoid arthritis (RA), a chronic inflammatory multisystem disorder marked by joint pain, stiffness, swelling and multiple systemic involvements, requires a multifaceted approach for its management. It includes symptomatic treatment with analgesics as well as disease-modifying medications to alter the course
S Noble et al.
Drugs, 51(3), 424-430 (1996-03-01)
Meloxicam is a new nonsteroidal anti-inflammatory drug (NSAID) developed for the treatment of rheumatoid arthritis and osteoarthritis. It has greater in vitro and in vivo inhibitory action against the inducible isoform of cyclo-oxygenase (COX-2), which is implicated in the inflammatory
Relative value of the NSAIDs, including COX-2 inhibitors and meloxicam.
Frederic R Curtiss
Journal of managed care pharmacy : JMCP, 12(3), 265-268 (2006-04-21)
D E Furst
Seminars in arthritis and rheumatism, 26(6 Suppl 1), 21-27 (1997-06-01)
Nonsteroidal antiinflammatory drugs (NSAIDs) exert their actions by inhibiting cyclooxygenase (COX). It has recently been postulated that NSAIDs' antiinflammatory efficacy arises from inhibition of the COX-2 isoform of cyclooxygenase, whereas inhibition of the COX-1 isoform produces the troublesome and sometimes
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