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Merck
CN

1430101

USP

Methyl ethyl ketone

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

2-Butanone, Ethyl methyl ketone, MEK, Methyl ethyl ketone

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About This Item

Linear Formula:
C2H5COCH3
CAS Number:
78-93-3
Molecular Weight:
72.11
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329750439
MDL number:
MFCD00011648
Beilstein/REAXYS Number:
741880

Key Documents

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Product Name

Methyl ethyl ketone, United States Pharmacopeia (USP) Reference Standard

InChI key

ZWEHNKRNPOVVGH-UHFFFAOYSA-N

SMILES string

CC(CC)=O

InChI

1S/C4H8O/c1-3-4(2)5/h3H2,1-2H3

grade

pharmaceutical primary standard

vapor density

2.49 (vs air)

vapor pressure

71 mmHg ( 20 °C)

form

liquid

autoignition temp.

960 °F

expl. lim.

10.1 %

manufacturer/tradename

USP

refractive index

n20/D 1.379 (lit.)

bp

80 °C (lit.)

mp

−87 °C (lit.)

density

0.805 g/mL at 25 °C (lit.)

application(s)

USP Biologics
pharmaceutical (small molecule)

format

neat

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Methyl ethyl ketone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Ethyl Acetate

General description

Methyl ethyl ketone is a solvent used in biologic and pharmaceutical applications. Its role is particularly crucial in the extraction and purification of biologic compounds, as well as in formulations where its quick evaporation properties help ensure product stability. MEK is valuable in the preparation of drug delivery systems, contributing to the efficient dissolution of active pharmaceutical ingredients.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.
This product is part of USP Biologics Program.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pha
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

EUH066

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

30.2 °F - closed cup

flash_point_c

-1 °C - closed cup

Regulatory Information

危险化学品
易制毒化学品（3类）
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