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Merck
CN

1461003

USP

Niacin

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Nicotinic acid, 3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B3

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About This Item

Empirical Formula (Hill Notation):
C6H5NO2
CAS Number:
59-67-6
Molecular Weight:
123.11
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329750552
MDL number:
MFCD00006391
Beilstein/REAXYS Number:
109591

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Product Name

Niacin, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

SMILES string

OC(=O)c1cccnc1

InChI key

PVNIIMVLHYAWGP-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

nicotinic acid

manufacturer/tradename

USP

technique(s)

HPLC: suitable

mp

236-239 °C (lit.)

solubility

ethanol: 12.5 g/L at 25 °C
water: soluble 180 g/L at 20 °C

density

1.473 g/cm3 at 25 °C

application(s)

pharmaceutical (small molecule)

format

neat

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Niacin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Niacin Tablets
  • Niacin Injection
  • Niacin Extended-Release Tablets
  • Inositol Niacinate
  • Niacinamide
  • Water-Soluble Vitamins Capsules

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

379.4 °F - closed cup

flash_point_c

193 °C - closed cup

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Niacin
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(5), 3138-3138 (2020)
Niacin Extended-Release Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(4), 3141-3141 (2020)
Oil- and Water-Soluble Vitamins Capsules
United States Pharmacopeia, 40(5), 5389-5389 (2017)
Water-Soluble Vitamins Capsules
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(5), 5499-5499 (2016)
NIACIN OR NIACINAMIDE ASSAY
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(5), 6704-6704 (2014)
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