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About This Item
Empirical Formula (Hill Notation):
C8H6N4O5
CAS Number:
Molecular Weight:
238.16
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
893207
InChI key
NXFQHRVNIOXGAQ-YCRREMRBSA-N
SMILES string
[O-][N+](=O)c1ccc(\C=N\N2CC(=O)NC2=O)o1
InChI
1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)/b9-3+
grade
pharmaceutical primary standard
API family
nitrofurantoin
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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Reappraisal of the risk/benefit of nitrofurantoin: review of toxicity and efficacy.
R R Shah et al.
Adverse drug reactions and acute poisoning reviews, 8(4), 183-201 (1989-01-01)
K A Boggess et al.
Obstetrical & gynecological survey, 51(6), 367-370 (1996-06-01)
Acute pulmonary reactions to nitrofurantoin are an uncommon side effect of therapy and can cause minor or life-threatening pulmonary dysfunction. Symptoms include fever, chills, cough, pleuritic chest pain, dyspnea. Rarely, pleural effusion and/or pulmonary hemorrhage may occur. Diagnosis is made
Guy Amit et al.
The Israel Medical Association journal : IMAJ, 4(3), 184-186 (2002-03-23)
Nitrofurantoin is a commonly prescribed urinary antiseptic. Hepatic injury has been associated with its use. To present three patients in whom long-term exposure to the drug resulted in chronic active hepatitis; and to review the epidemiology, clinical immunology, histopathology, pathogenetic
L A Paiva et al.
The American journal of gastroenterology, 87(7), 891-893 (1992-07-01)
Nitrofurantoin-induced hepatic injury has been established unequivocally as an entity by rechallenge experiences. We reviewed 12 previously reported cases in which rechallenge was described. The longest reported interval between initial injury and rechallenge-provoked injury was 4 yr. We report a
Edward Karpman et al.
The Journal of urology, 172(2), 448-453 (2004-07-13)
Many children with urological disease require long-term treatment with antibiotics. In many cases the choice of medical instead of surgical management hinges on the implied safety of certain drugs. Recently some groups have advocated subureteral injection procedures to avoid long-term
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