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1538505

USP

Pilocarpine

Name: Pilocarpine
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

cis-3-Ethyl-4-(1-methyl-5-imidazolylmethyl)dihydro-2(3H)-furanone

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₆N₂O₂

CAS Number:

92-13-7

Molecular Weight:

208.26

UNSPSC Code:

41116107

NACRES:

NA.24

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Properties

grade

pharmaceutical primary standard

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/C11H16N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10-/m0/s1

InChI key

QCHFTSOMWOSFHM-WPRPVWTQSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pilocarpine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

pictograms

GHS06

signalword

Danger

hcodes

H300 + H330

pcodes

P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Ascorbic acid ameliorates seizures and brain damage in rats through inhibiting autophagy.

Yan Dong et al.

Brain research, 1535, 115-123 (2013-09-03)

Oxidative stress is a mechanism of cell death induced by seizures. Antioxidant compounds have neuroprotective effects due to their ability to inhibit free radical production. Autophagy is a process in which cytoplasmic components such as organelles and proteins are delivered

Biodegradable in situ gelling delivery systems containing pilocarpine as new antiglaucoma formulations: effect of a mercaptoacetic acid/N-isopropylacrylamide molar ratio.

Jui-Yang Lai

Drug design, development and therapy, 7, 1273-1285 (2013-11-05)

Ocular drug delivery is one of the most commonly used treatment modalities in the management of glaucoma. We have recently proposed the use of gelatin and poly(N-isopropylacrylamide) (PNIPAAm) graft copolymers as biodegradable in situ forming delivery systems for the intracameral

Impaired D-serine-mediated cotransmission mediates cognitive dysfunction in epilepsy.

Katharina Klatte et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(32), 13066-13080 (2013-08-09)

The modulation of synaptic plasticity by NMDA receptor (NMDAR)-mediated processes is essential for many forms of learning and memory. Activation of NMDARs by glutamate requires the binding of a coagonist to a regulatory site of the receptor. In many forebrain

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Global Trade Item Number

SKU	GTIN
1538505-300MG	04061838741189