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Merck
CN

1539009

USP

Pilocarpine nitrate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Pilocarpine nitrate salt

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About This Item

Empirical Formula (Hill Notation):
C11H16N2O2 · HNO3
CAS Number:
148-72-1
Molecular Weight:
271.27
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329750841
MDL number:
MFCD00078497
Beilstein/REAXYS Number:
4171406

Key Documents

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SMILES string

O[N+]([O-])=O.CC[C@H]1[C@H](COC1=O)Cc2cncn2C

InChI key

PRZXEPJJHQYOGF-GNAZCLTHSA-N

InChI

1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1

grade

pharmaceutical primary standard

API family

pilocarpine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... CHRM1(1128), CHRM3(1131)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pilocarpine nitrate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Pilocarpine
  • Pilocarpine Nitrate
  • Pilocarpine Nitrate Ophthalmic Solution

Biochem/physiol Actions

Nonselective muscarinic acetylcholine receptor agonist.
Nonselective muscarinic acetylcholine receptor agonist; used to produce an experimental model of epilepsy.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Flame over circleSkull and crossbones
GHS03,GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Ox. Sol. 2

Storage Class

5.1B - Oxidizing hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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