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关于此项目
经验公式（希尔记法）:
C43H68ClNO11
化学文摘社编号:
分子量:
810.45
MDL number:
NACRES:
NA.24
UNSPSC Code:
41116107
grade
pharmaceutical primary standard
agency
USP
manufacturer/tradename
USP
application(s)
pharmaceutical small molecule
format
neat
storage temp.
2-8°C
SMILES string
C[C@H]([C@@H](O)CC([C@H](CC)/C=C1C)=O)[C@](/C(C)=C/[C@@]2([H])C[C@@H](OC)[C@@H](Cl)CC2)([H])OC([C@@]3([H])N(C(C([C@@]4(O)[C@H](C)C[C@H](OC)[C@@H]([C@@H](OC)C[C@@H](C)C\1)O4)=O)=O)CCCC3)=O
InChI
1S/C43H68ClNO11/c1-10-30-18-24(2)17-25(3)19-36(53-8)39-37(54-9)21-27(5)43(51,56-39)40(48)41(49)45-16-12-11-13-32(45)42(50)55-38(28(6)33(46)23-34(30)47)26(4)20-29-14-15-31(44)35(22-29)52-7/h18,20,25,27-33,35-39,46,51H,10-17,19,21-23H2,1-9H3/b24-18+,26-20+/t25-,27+,28+,29-,30+,31-,32-,33-,35+,36-,37-,38+,39+,43+/m0/s1
InChI key
KASDHRXLYQOAKZ-XDSKOBMDSA-N
General description
Find answers to frequently asked questions on USP products in USP FAQs.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Biochem/physiol Actions
吡美莫司，也称为吡咯莫司，是一种大内酰胺类子囊霉素衍生物，可起到免疫抑制的作用。它可与巨噬蛋白12（FKBP-12）发生高亲和力结合，并可抑制钙调磷酸酶（一种钙依赖磷酸酶）。吡美莫司可抑制T细胞和肥大细胞产生促炎性细胞因子，并阻止肥大细胞释放炎性细胞因子和介体。临床上已将其用作湿疹的治疗。
钙调神经磷酸酶抑制剂，免疫抑制剂
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
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