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Merck
CN

1572208

USP

Propionic acid

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Acid C3, Propanoic acid, Propanyl acid

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About This Item

Linear Formula:
CH3CH2COOH
CAS Number:
79-09-4
Molecular Weight:
74.08
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329750985
MDL number:
MFCD00002756
Beilstein/REAXYS Number:
506071

Key Documents

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Product Name

Propionic acid, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)

SMILES string

CCC(O)=O

InChI key

XBDQKXXYIPTUBI-UHFFFAOYSA-N

grade

pharmaceutical primary standard

vapor density

2.55 (vs air)

vapor pressure

2.4 mmHg ( 20 °C)

API family

propionic acid

autoignition temp.

955 °F

expl. lim.

12.1 %

manufacturer/tradename

USP

refractive index

n20/D 1.386 (lit.)

bp

141 °C (lit.)

mp

−24-−23 °C (lit.)

density

0.993 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Propionic acid USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

General description

Propionic acid (PA) is a naturally occurring carboxylic acid, which in its pure state exists as a colorless corrosive liquid with an unpleasant odor. It is miscible in water. Industrially it is produced by hydrocarboxylation of ethylene in presence nickel carbonyl as a catalyst. PA has been found to reduce food intake, lower the fatty acids content in plasma and liver, might improve tissue insulin sensitivity and exerts immunosuppressive actions. Propionic acid is an excellent raw material as it is stable, cheap and safe and can even be used as a food additive.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

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Danger

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

129.2 °F - closed cup

flash_point_c

54 °C - closed cup

Regulatory Information

危险化学品
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Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms
Sa'ad, H., et al.
Molecular and Cellular Biology, 1801 (11), 1175-1183 (2010)
Nucleophilic ?-Carbon Activation of Propionic Acid as a 3-Carbon Synthon by Carbene Organocatalysis
Jin, Zhichao, et al.
Chemistry?A European Journal , 21 (26), 9360-9363 (2015)
Flour and Breads and their Fortification in Health and Disease Prevention.
Victor R. Preedy, Ronald Ross Watson, Vinood B
Technology & Engineering, 476-476 (2011)

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