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1707894

USP

Valacyclovir Related Compound G

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

4-(Dimethylamino)pyridine, N,N-Dimethylpyridin-4-amine, DMAP

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About This Item

Empirical Formula (Hill Notation):
C7H10N2
CAS Number:
1122-58-3
Molecular Weight:
122.17
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329751470
MDL number:
MFCD00006418
Beilstein/REAXYS Number:
110354
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grade

pharmaceutical primary standard

API family

valacyclovir

manufacturer/tradename

USP

mp

108-110 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CN(C)c1ccncc1

InChI

1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3

InChI key

VHYFNPMBLIVWCW-UHFFFAOYSA-N

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General description

Valacyclovir Related Compound G, also called as 4-(Dimethylamino)pyridine (DMAP) is an excellent catalyst for acylation of hindered alcohols and in chemical transformations. It is highly nucleophilic in nature.

Application

A highly efficient catalyst for acylation reactions
Valacyclovir Related Compound G USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Valacyclovir Hydrochloride

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 1

target_organs

Nervous system

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

255.2 °F

flash_point_c

124 °C

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Configurationally Stable Biaryl Analogues of 4-(Dimethylamino) pyridine: A Novel Class of Chiral Nucleophilic Catalysts.
Spivey, Alan C., et al.
The Journal of Organic Chemistry, 64.26, 9430-9443 (1999)
Masahiro Murakami et al.
Acta biomaterialia, 10(11), 4723-4729 (2014-07-20)
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Articles

Organic impurity profiling of Valacyclovir using TLC

Thin-layer chromatography method for detecting organic impurities in valacyclovir, an antiviral medication, following USP monograph guidelines.

Global Trade Item Number

SKUGTIN
1707894-50MG04061833855775

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