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Merck
CN

1713004

USP

Vinblastine sulfate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Vinblastine sulfate salt, Vincaleukoblastine, Sulfate (1:1) (salt), VLB, Vincaleukoblastine sulfate salt

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About This Item

Empirical Formula (Hill Notation):
C46H58N4O9 · H2SO4
CAS Number:
143-67-9
Molecular Weight:
909.05
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329751498
MDL number:
MFCD00082457
Beilstein/REAXYS Number:
3659812

Key Documents

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InChI key

KDQAABAKXDWYSZ-PNYVAJAMSA-N

InChI

1S/C46H58N4O9.H2O4S/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7;1-5(2,3)4/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3;(H2,1,2,3,4)/t28-,37-,38+,39+,42-,43+,44+,45-,46-;/m0./s1

SMILES string

OS(O)(=O)=O.[H][C@@]12CN(CCc3c([nH]c4ccccc34)[C@@](C1)(C(=O)OC)c5cc6c(cc5OC)N(C)[C@@]7([H])[C@](O)([C@H](OC(C)=O)[C@]8(CC)C=CCN9CC[C@]67[C@]89[H])C(=O)OC)C[C@](O)(CC)C2

grade

pharmaceutical primary standard

API family

vinblastine

manufacturer/tradename

USP

mp

267 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

Gene Information

human ... TUBA1A(7846), TUBA1B(10376), TUBA1C(84790), TUBA3C(7278), TUBA3E(112714), TUBA4A(7277), TUBB(203068), TUBB1(81027), TUBB2A(7280), TUBB2B(347733), TUBB3(10381), TUBB4A(10382), TUBB4B(10383), TUBB6(84617), TUBB8(347688)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Vinblastine sulfate USP reference standard for use in specified quality tests and assays.

Also used to prepare standard and system suitability solutions for the assay, according to the given below monographs of United States Pharmacopeia (USP):
  • Vinblastine Sulfate
  • Vincristine Sulfate
  • Vinblastine Sulfate for Injection
  • Vincristine Sulfate for Injection
  • Vincristine Sulfate Injection

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Muta. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

Regulatory Information

涉药品监管产品
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Vincristine Sulfate
United States Pharmacopeia, 45(4) (2020)
Vincristine Sulfate for Injection
United States Pharmacopeia, 47(2) (2022)
Vinblastine Sulfate for Injection
United States Pharmacopeia, 47(2) (2022)
Vincristine Sulfate Injection
United States Pharmacopeia, 47(2) (2022)
Vinblastine Sulfate
United States Pharmacopeia, 45(4) (2020)

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