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Merck
CN

1714007

USP

Vincristine sulfate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Vincristine sulfate salt, 22-Oxovincaleukoblastine sulfate salt, Leurocristine sulfate salt, VCR

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About This Item

Empirical Formula (Hill Notation):
C46H56N4O10 · H2SO4
CAS Number:
2068-78-2
Molecular Weight:
923.04
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329751500
MDL number:
MFCD00084729
Beilstein/REAXYS Number:
3924631

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InChI

1S/C46H56N4O10.H2O4S/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6;1-5(2,3)4/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3;(H2,1,2,3,4)/t28-,37-,38+,39+,42-,43+,44+,45-,46-;/m0./s1

SMILES string

OS(O)(=O)=O.CC[C@]1(O)CC2CN(CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C=O)C7[C@](O)([C@H](OC(C)=O)[C@]8(CC)C=CCN9CC[C@]67C89)C(=O)OC)C1

InChI key

AQTQHPDCURKLKT-PNYVAJAMSA-N

grade

pharmaceutical primary standard

API family

vincristine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Vincristine sulfate USP reference standard intended for use in specified compendial tests and assays.

Also used to prepare standard and system-suitability solutions for the identification and assay according to the given below monographs of United States Pharmacopeia (USP):
  • Vincristine Sulfate for Injection
  • Vincristine Sulfate
  • Vincristine Sulfate Injection
  • Vinblastine Sulfate

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Muta. 2 - Repr. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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Vincristine Sulfate for Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 47(2) (2022)
Vinblastine Sulfate
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 45(4) (2020)
Vincristine Sulfate Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 47(2) (2022)
Vincristine Sulfate
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 45(4) (2020)

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