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Merck
CN

1A00720

USP

Desiodoamiodarone

Pharmaceutical Analytical Impurity (PAI)

Synonym(s):

(2-Butylbenzofuran-3-yl)[4-[2-(diethylamino)ethoxy]phenyl]methanone, Desiodoamiodarone

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About This Item

Empirical Formula (Hill Notation):
C25H31NO3
CAS Number:
23551-25-9
Molecular Weight:
393.52
UNSPSC Code:
12352200
MDL number:
MFCD24682757
NACRES:
NA.24

Key Documents

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SMILES string

N(CCOc1ccc(cc1)C(=O)c2c3c([o]c2CCCC)cccc3)(CC)CC

InChI

1S/C25H31NO3/c1-4-7-11-23-24(21-10-8-9-12-22(21)29-23)25(27)19-13-15-20(16-14-19)28-18-17-26(5-2)6-3/h8-10,12-16H,4-7,11,17-18H2,1-3H3

InChI key

PNZXBMCTFUFPLR-UHFFFAOYSA-N

grade

pharmaceutical analytical impurity (PAI)

agency

USP

API family

amiodarone

manufacturer/tradename

USP

application(s)

pharmaceutical small molecule

format

neat

storage temp.

2-8°C

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Related Categories

General description

Desiodoamiodarone is a USP Pharmaceutical Analytical Impurity (PAI).
USP PAI are a product line of impurities suitable for research and analytical purposes, which help to ensure the quality and safety of medicines.
Associated Drug Substance: Amiodarone
Therapeutic Area: Cardiovascular

Application

Desiodoamiodarone (USP PAI) is intended for use in analytical testing to detect, identify, and measure pharmaceutical impurities.

Features and Benefits

USP PAI advance your early analytical R&D and process development. PAI can be used in the following applications:
1. Conduct analytical tests during early formulation feasibility studies.
2. Determine degradation impurities produced during stress studies.
3. Develop, validate, and transfer analytical methods.
4. Perform spiking studies during process R&D to demonstrate depletion upon recrystallization.
5. Record retention times and/or spectra
6. Determine relative response factors.
7. Identify unknown impurities that formed during ICH stability conditions.
8. Identify impurities that are present in the Reference Listed Drug
9. Test for and profile impurities not listed in drug substance and drug product monographs.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  

Other Notes

Sales restrictions may apply.
USP issued SDS can be found here

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Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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